# Case Report: Intrahepatic arterioportal fistula (IAPF)—a rare cause of hemobilia

**Authors:** Ye Wang, Wangde Jin, Xu Jiang, Xinglin Jin

PMC · DOI: 10.3389/fmed.2026.1777550 · Frontiers in Medicine · 2026-02-23

## TL;DR

This case report describes a rare instance of biliary bleeding caused by an intrahepatic arterioportal fistula in an elderly woman and highlights the role of imaging in diagnosis and treatment.

## Contribution

The novelty lies in presenting a rare cause of hemobilia and demonstrating the effectiveness of imaging and embolization in managing it.

## Key findings

- Intrahepatic arterioportal fistula was identified as the cause of hemobilia through CT and MRCP imaging.
- Transcatheter arterial embolization successfully treated the fistula and stopped the bleeding.
- The case emphasizes the diagnostic value of imaging in complex biliary diseases in elderly patients.

## Abstract

Intrahepatic arterioportal fistula is a rare vascular malformation, and cases of hemobilia due to it are extremely rare. This article reports a rare case of hemobilia due to intrahepatic arterioportal fistula in an elderly woman. Upon admission, the patient presented with sporadic upper abdominal pain lasting 3 days. The initial diagnosis of choledocholithiasis was made following a review of the upper abdominal Computed Tomography (CT) scan from a previous hospital and our hospital's Magnetic Resonance Cholangiopancreatography (MRCP). Hemobilia and sedimentary clot were identified during ERCP microscopy. Post-ERCP imaging, specifically CT enhancement, revealed an intrahepatic arterioportal fistula. This finding, in conjunction with insights from a multidisciplinary consultation, led to treatment via transcatheter arterial embolization (TAE). The patient recovered well postoperatively with cessation of bleeding. This case demonstrates IAPF as a rare cause of biliary bleeding and the diagnostic value of imaging for IAPF, which provides reference for the diagnosis and treatment of complex biliary diseases in elderly patients.

## Linked entities

- **Diseases:** choledocholithiasis (MONDO:0006699)

## Full-text entities

- **Genes:** SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, GGTLC5P (gamma-glutamyltransferase light chain 5 pseudogene) [NCBI Gene 653590] {aka GGT}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, ALPP (alkaline phosphatase, placental) [NCBI Gene 250] {aka ALP, PALP, PLAP, PLAP-1}, GGT1 (gamma-glutamyltransferase 1) [NCBI Gene 2678] {aka CD224, D22S672, D22S732, GGT, GGT 1, GGTD}
- **Diseases:** choledocholithiasis (MESH:D042883), hypertension (MESH:D006973), melena (MESH:D008551), trauma (MESH:D014947), liver diseases (MESH:D008107), portal hypertension (MESH:D006975), cirrhosis (MESH:D005355), varicose veins (MESH:D014648), erosions (MESH:D014077), stone (MESH:D007669), abdominal pain (MESH:D015746), ulcers (MESH:D014456), hepatosplenomegaly (MESH:C535727), spider nevi (MESH:D009506), pseudoaneurysms (MESH:D017541), malignancy (MESH:D009369), cerebral infarction (MESH:D002544), hepatic function abnormalities (MESH:D056486), Vascular malformations (MESH:D054079), tenderness (MESH:D063806), heart disease (MESH:D006331), biliary diseases (MESH:D001660), developmental anomalies (MESH:C566440), abdominal trauma (MESH:D000007), bleeding (MESH:D006470), arteriovenous fistula (MESH:D001164), gastrointestinal bleeding (MESH:D006471), HB (MESH:D006431), muscle rigidity (MESH:D009127), CIAPF (MESH:D005402)
- **Chemicals:** bilirubin (MESH:D001663)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12968218/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12968218/full.md

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Source: https://tomesphere.com/paper/PMC12968218