# An Intraoperative Fluoroscopic Predictor of Successful Micra Implantation on the Right Ventricular Mid‐Septum

**Authors:** Misun Pak, Ken Kakita, Takashi Yamasaki, Tetsuhisa Hattori

PMC · DOI: 10.1002/joa3.70307 · Journal of Arrhythmia · 2026-03-08

## TL;DR

This study identifies a fluoroscopic marker, the α-loop shape of the delivery catheter, that predicts successful implantation of the Micra device in the right ventricular mid-septum.

## Contribution

The study introduces the α-loop shape as a novel intraoperative fluoroscopic predictor for successful mid-septal Micra implantation.

## Key findings

- The α-loop shape of the delivery catheter was more frequent in mid-septal implantation cases.
- Multivariable analysis identified the α-loop shape as an independent predictor of mid-septal implantation.
- Computed tomography confirmed the device position in 59 patients, revealing implantation site distributions.

## Abstract

The Micra transcatheter pacing system has been adopted globally. However, the procedural parameters for safe Micra implantation on the ventricular wall, particularly in the mid‐septum, remain unknown. This study aimed to identify the predictors of Micra implantation on the ventricular mid‐septum.

We retrospectively analyzed patients who underwent Micra implantation and had computed tomography (CT) after implantation to confirm the device position. Patients were classified into mid‐septum and non–mid‐septum groups based on CT findings. To explore predictors associated with mid‐septal implantation, fluoroscopic parameters in the standard left anterior oblique (LAO) view were evaluated during implantation, including the presence of an α‐loop shape of the delivery catheter and the angle between the axis of the device cup and the tangent of the ventricular septum (angle θ). Logistic regression analysis was performed to identify predictors of mid‐septal Micra implantation.

Of 119 patients who underwent Micra implantation, 59 had CT confirmation. Among them, 31 (52.5%) had mid‐septal, 18 (30.5%) apical septal, and 10 (17.0%) free wall implantation. Since no cases involved basal septal positioning, the non–mid‐septum group consisted of apical septal and free wall implantations. The angle θ was significantly larger and the α‐loop shape of the catheter was more frequent in the mid‐septum group. However, multivariable analysis identified only the α‐loop shape as an independent predictor of mid‐septal implantation (adjusted odds ratio, 5.10; 95% CI, 1.40–20.7; p = 0.016).

An α‐loop shape of the delivery catheter may serve as a practical fluoroscopic marker for successful mid‐septal Micra implantation.

Fluoroscopic predictors of successful mid‐septal Micra implantation were evaluated using computed tomography confirmation. Among fluoroscopic parameters assessed in the left anterior oblique view, the presence of an α‐loop shape of the delivery catheter was independently associated with mid‐septal implantation. An α‐loop configuration may serve as a practical intraoperative marker for achieving mid‐septal Micra placement.

## Full-text entities

- **Genes:** NPPB (natriuretic peptide B) [NCBI Gene 4879] {aka BNP, Iso-ANP}
- **Diseases:** PICM (MESH:D009202), stenosis (MESH:D003251), sick sinus syndrome (MESH:D012804), torsion (MESH:D050723), skeletal deformities (MESH:D009140), impaired renal function (MESH:D007674), heart failure (MESH:D006333), cardiac effusion (MESH:D006331), malformations (MESH:C564254), thrombus (MESH:D013927), venous occlusion (MESH:D001157), infection (MESH:D007239), atrial fibrillation (MESH:D001281), Atrioventricular block (MESH:D054537)
- **Chemicals:** nitinol (MESH:C013616), LAO (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12968048/full.md

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Source: https://tomesphere.com/paper/PMC12968048