# The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

## TL;DR

This study shows that a probiotic containing Bifidobacterium bifidum can positively affect the gut microbiome of obese individuals.

## Contribution

The novel finding is the specific positive impact of Bifidobacterium bifidum on several gut bacteria in obese individuals.

## Key findings

- The probiotic supplement increased the abundance of beneficial gut bacteria like Bacteroides uniformis and Alistipes putredinis.
- The study suggests Bifidobacterium bifidum may help treat gut microbiota dysbiosis in obesity.

## Abstract

It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to investigate the effect of a probiotic supplement containing Bifidobacterium bifidum on the intestinal microbiome of people with obesity using high-throughput sequencing on the DNBSEQ-G50 platform. The study demonstrated a positive effect of the supplement on bacterial species such as Bacteroides uniformis, Alistipes putredinis, Alistipes shahii, Dysosmobacter welbionis, and Gemmiger formicilis. Therefore, we suggest the potential use of this bacterial species in the treatment of gut microbiota dysbiosis of obese individuals.