# A neutrosophic explainable AI framework for modeling uncertainty in immersive stereotactic neurosurgical simulation

**Authors:** Jesus Rafael Hechavarria-Hernandez

PMC · DOI: 10.3389/fneur.2026.1766089 · Frontiers in Neurology · 2026-02-23

## TL;DR

This paper introduces a new AI framework that better assesses surgical skills in VR simulations by accounting for uncertainty and instability.

## Contribution

The novel Neutrosophic Explainable AI framework models surgical performance with truth, indeterminacy, and falsity dimensions.

## Key findings

- The framework successfully differentiated expert, indeterminate, and novice skill groups.
- It identified high-risk cases with acceptable accuracy but significant instability, which traditional metrics miss.

## Abstract

The integration of Artificial Intelligence (AI) and Virtual Reality (VR) has transformed medical education; however, performance assessment in high-stakes fields such as stereotactic neurosurgery remains largely dependent on binary or threshold-based metrics. In procedures such as deep brain stimulation (DBS), where safety margins are below 2 mm, these approaches fail to capture indeterminate behaviors, including hesitation, micro-instability, and unstable trajectories, potentially leading to false-positive competence classifications. This study introduces a Neutrosophic Explainable AI (N-XAI) framework that models surgical performance through three independent dimensions: truth (competence), Indeterminacy (instability/ambiguity), and Falsity (error). Performance is represented in a two-dimensional precision–stability space and quantified using single-valued neutrosophic sets (SVNS). For theoretical validation, a synthetic dataset comprising 60 simulated surgical attempts distributed across three skill groups (expert, indeterminate, and novice) was generated. Neutrosophic competence scores were computed and analyzed using non-parametric statistical tests. The framework successfully differentiated the three groups and identified indeterminate, high-risk cases that achieved acceptable spatial accuracy but exhibited significant instability—patterns that conventional metrics fail to detect. The proposed N-XAI framework provides a mathematically grounded and interpretable approach for modeling uncertainty in immersive neurosurgical simulation. By explicitly accounting for indeterminacy, it enhances the diagnostic value of VR-based training systems and lays the groundwork for future validation in live stereotactic simulation environments.

## Full-text entities

- **Diseases:** movement disorders (MESH:D009069), XAI (MESH:C538243), depression (MESH:D003866), obsessive-compulsive disorder (MESH:D009771), AI (MESH:C538142), fatigue (MESH:D005221), COVID-19 (MESH:D000086382), Tremor (MESH:D014202), Parkinson's disease (MESH:D010300)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12967968/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC12967968/full.md

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Source: https://tomesphere.com/paper/PMC12967968