# Trend in Hospital Admissions for Cardiovascular Diseases (CVDs) Before and During the Coronavirus Disease 2019 (COVID‐19) Pandemic: A Retrospective Analysis From a Sub‐Urban Area in Sub‐Saharan Africa

**Authors:** Konfo Gaetan Kwasseu, Clovis Nkoke, B. F. Kuaguim Kenfack, Dzudie Anastase

PMC · DOI: 10.1002/hsr2.71993 · Health Science Reports · 2026-03-08

## TL;DR

This study examines how hospital admissions for heart diseases changed in Cameroon before and during the COVID-19 pandemic.

## Contribution

The study provides new data on CVD admissions and outcomes in Sub-Saharan Africa during the pandemic.

## Key findings

- CVD admissions showed a downward trend during the pandemic compared to the pre-pandemic period.
- Admissions for Acute Myocardial Infarction decreased the most during the first wave of the pandemic.
- In-hospital mortality for CVDs increased slightly but not significantly during the pandemic.

## Abstract

The COVID‐19 pandemic was a global public concern and constitutes a future threat to the world population due to its indirect effect on the burden of non‐communicable diseases. The pandemic manifested disruptions in healthcare delivery and access. However, there is limited data in Sub‐Saharan Africa on the impact of COVID‐19 on cardiovascular disease (CVD) admissions and outcomes. This study aimed to compare the trends of CVD admissions and outcomes before and during the COVID‐19 pandemic in the Southwest Region of Cameroon.

We carried out a retrospective study of patients suffering from CVDs admitted from March 11, 2018, to March 11, 2020 (Pre‐COVID‐19 pandemic period) and from March 11, 2020, to March 11, 2022 (COVID‐19 pandemic period). A p‐value < 0.05 was considered statistically significant.

There were 483 admissions due to CVD during the COVID‐19 pandemic and 518 during the pre‐COVID‐19 period. There was no significant difference in mean age before (57.97 ± 15.6 years) and during the pandemic (59.74 ± 16.1 years) (p = 0.44). There was also no significant change in the proportion of males and females during and before the pandemic: males (21, 4%, and 24.8%), and females (26.8% and 27%), (p = 0.28). There was a downward secular trend with random variation in the number of CVD admissions during the pandemic compared with the corresponding pre‐COVID period, which had an upward trend. Rates of admissions of Acute Myocardial Infarction decreased the most (22.2%) during the first wave of the pandemic. The in‐hospital mortality increased by 2.4% with a relative risk for Mortality of 1.18 (95% CI [0.87–1.61], p = 0.28). There was no change in median length of hospital stay (p = 0.936).

This study provides evidence of a decreasing tendency in admissions due to CVD during the COVID‐19 Pandemic at the BRH. The effects varied among the different types of CVDs. The in‐hospital mortality of CVDs did not change significantly.

## Linked entities

- **Diseases:** Coronavirus Disease 2019 (MONDO:0100096), Acute Myocardial Infarction (MONDO:0004781)

## Full-text entities

- **Genes:** ACE2 (angiotensin converting enzyme 2) [NCBI Gene 59272] {aka ACEH}, FGB (fibrinogen beta chain) [NCBI Gene 2244] {aka HEL-S-78p}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}, IL7 (interleukin 7) [NCBI Gene 3574] {aka IL-7, IMD130}, IL2 (interleukin 2) [NCBI Gene 3558] {aka IL-2, TCGF, lymphokine}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, CD8A (CD8 subunit alpha) [NCBI Gene 925] {aka CD8, CD8alpha, IMD116, Leu2, p32}
- **Diseases:** obesity (MESH:D009765), arrhythmias (MESH:D001145), NCDs (MESH:D000073296), hypercoagulability (MESH:D019851), myocarditis (MESH:D009205), stroke (MESH:D020521), myocardial injury (MESH:D009202), acute MI (MESH:D000208), hyperlipidemia (MESH:D006949), inflammation (MESH:D007249), disease (MESH:D004194), coronary heart disease (MESH:D003327), ACS (MESH:D054058), diabetes (MESH:D003920), endothelial dysfunction (MESH:D014652), abnormalities in glucose metabolism (MESH:D044882), cardiac arrest (MESH:D006323), Heart failure (MESH:D006333), cytokine storm (MESH:D000080424), heart disease (MESH:D006331), long COVID (MESH:D000094024), pericarditis (MESH:D010493), Viral infections (MESH:D014777), death (MESH:D003643), venous thromboembolism (MESH:D054556), hypertension (MESH:D006973), COVID-19 (MESH:D000086382), infection (MESH:D007239), coagulation disturbances (MESH:D001778), CVD (MESH:D002318), AMI (MESH:D009203), pericardial disease (MESH:D008476), cardio-cerebrovascular disease (MESH:D002561)
- **Chemicals:** lipid (MESH:D008055), d (MESH:D003903)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Nicotiana tabacum (American tobacco, species) [taxon 4097], Severe acute respiratory syndrome-related coronavirus (no rank) [taxon 694009], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12967670/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12967670/full.md

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Source: https://tomesphere.com/paper/PMC12967670