# Delivering Lifesaving Thrombolysis for Acute Myocardial Infarction in an Underserved Region of Ghana: Lessons From the First Successful Case

**Authors:** Abednego Attoh, Abdul-Subulr Yakubu, Dominic Akansiadi Akaateba, John Chukwuebuka Ota, Klein Khol Bezeng

PMC · DOI: 10.7759/cureus.103036 · Cureus · 2026-02-05

## TL;DR

This paper discusses the challenges and lessons learned from successfully delivering thrombolysis for a heart attack patient in a region of Ghana with limited medical resources.

## Contribution

The paper presents the first successful thrombolysis case in northern Ghana, offering practical insights for improving acute myocardial infarction management in underserved areas.

## Key findings

- Thrombolysis is underutilized in northern Ghana due to significant logistical and systemic barriers.
- A successful thrombolysis case was managed despite routine challenges in the region.
- The case highlights opportunities for improving acute myocardial infarction care in resource-limited settings.

## Abstract

The management of acute coronary syndrome in northern Ghana is constrained. This is because no facility offers percutaneous coronary intervention. Thrombolysis is the only feasible reperfusion option, yet it remains significantly underutilized due to numerous barriers. In this case report, we describe the management of a 53-year-old man with ST-elevation myocardial infarction, highlighting the routine challenges faced in treating such patients in northern Ghana and identifying opportunities for improvement.

## Linked entities

- **Diseases:** acute myocardial infarction (MONDO:0004781), ST-elevation myocardial infarction (MONDO:0041656)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), deaths (MESH:D003643), akinetic (MESH:D018476), Acute Myocardial Infarction (MESH:D009203), Cardiovascular diseases (MESH:D002318), ischemic heart disease (MESH:D017202), cardiac conditions (MESH:D006331), adiposity (MESH:D018205), sinus tachycardia (MESH:D013616), myocardial necrosis (MESH:D009336), pain (MESH:D010146), acute coronary syndrome (MESH:D054058), edema (MESH:D004487), dyspnea (MESH:D004417), chest pain (MESH:D002637), diastolic dysfunction (MESH:D018487), -elevation myocardial infarction (MESH:D000072657), mitral regurgitation (MESH:D008944)
- **Chemicals:** atorvastatin (MESH:D000069059), glyceryl nitrate (-), clopidogrel (MESH:D000077144), oxygen (MESH:D010100), carvedilol (MESH:D000077261), lisinopril (MESH:D017706), empagliflozin (MESH:C570240), aspirin (MESH:D001241), blood glucose (MESH:D001786), enoxaparin (MESH:D017984)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12967205/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12967205/full.md

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Source: https://tomesphere.com/paper/PMC12967205