# Expanding the Spectrum of Uropathogens: A Rare Human Urinary Tract Infection by Rodentibacter pneumotropicus

**Authors:** Harish Prabhu, Madhuri Harshan

PMC · DOI: 10.7759/cureus.103004 · Cureus · 2026-02-05

## TL;DR

A rare urinary tract infection caused by Rodentibacter pneumotropicus, previously known as Pasteurella pneumotropica, is reported in a man with multiple health issues.

## Contribution

This is the first reported case of human urinary tract infection caused by Rodentibacter pneumotropicus.

## Key findings

- A 56-year-old man with chronic health conditions had a UTI caused by Pasteurella pneumotropica.
- The infection highlights the potential for this rodent-associated bacterium to cause disease in humans.
- The case emphasizes the importance of clinical awareness and antimicrobial stewardship for rare pathogens.

## Abstract

Pasteurella pneumotropica (now reclassified as Rodentibacter pneumotropicus) is a gram-negative coccobacillus primarily associated with rodents, with human infections being exceedingly rare. We report an unusual case of urinary tract infection (UTI) caused by P. pneumotropica in a 56-year-old man with multiple comorbidities, including chronic kidney disease (CKD), type 2 diabetes mellitus, systemic hypertension, and coronary artery disease (status post pacemaker insertion), who experienced multiple episodes of urinary tract Infection over a period of two years. His latest urine culture revealed growth of Pasteurella pneumotropica, a rare zoonotic gram-negative organism not commonly implicated in human disease. This case contributes to expanding the current understanding of human infections caused by Rodentibacter pneumotropicus, emphasizing the need for clinical awareness, microbiological vigilance, and careful antimicrobial stewardship.

## Linked entities

- **Diseases:** chronic kidney disease (MONDO:0005300), type 2 diabetes mellitus (MONDO:0005148), coronary artery disease (MONDO:0005010), urinary tract infection (MONDO:0005247)
- **Species:** Rodentibacter pneumotropicus (taxon 758)

## Full-text entities

- **Diseases:** type 2 diabetes mellitus (MESH:D003924), rhinitis (MESH:D012220), coronary artery disease (MESH:D003324), osteomyelitis (MESH:D010019), septic arthritis (MESH:D001170), urinary tract abnormalities (MESH:D014570), pyuria (MESH:D011776), septicemia (MESH:D018805), prostatic abscess (MESH:D011472), hypertension (MESH:D006973), Pasteurella infection (MESH:D010326), conjunctivitis (MESH:D003231), infection (MESH:D007239), stage 3 chronic kidney disease (MESH:D007676), renal calculi (MESH:D007669), UTI (MESH:D014552), leukocytosis (MESH:D007964), BPH (MESH:D011470), pneumonia (MESH:D011014), fever (MESH:D005334), otitis media (MESH:D010033), mastitis (MESH:D008413), dysuria (MESH:D053159), diabetes (MESH:D003920), urinary calculi (MESH:D014545), CKD (MESH:D051436)
- **Chemicals:** creatinine (MESH:D003404), penicillin (MESH:D010406), fosfomycin (MESH:D005578), cephalosporins (MESH:D002511), ceftriaxone (MESH:D002443), macrolides (MESH:D018942), fluoroquinolones (MESH:D024841), salt (MESH:D012492)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Klebsiella pneumoniae subsp. ozaenae (subspecies) [taxon 574], Felis catus (cat, species) [taxon 9685], Proteus mirabilis (species) [taxon 584], Homo sapiens (human, species) [taxon 9606], Rodentibacter pneumotropicus (species) [taxon 758], Pasteurella (genus) [taxon 745], Escherichia coli (E. coli, species) [taxon 562], Mus musculus (house mouse, species) [taxon 10090], Pseudomonas aeruginosa (species) [taxon 287], Klebsiella pneumoniae (species) [taxon 573], Canis lupus familiaris (dog, subspecies) [taxon 9615]
- **Mutations:** A1C

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12966883/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12966883/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12966883/full.md

---
Source: https://tomesphere.com/paper/PMC12966883