# Recurrent ileocolic variceal hemorrhage treated with superselective Onyx embolization: A case report

**Authors:** Mohammad Reza Babaei, Fatemeh Vaezi, Bahman Rasuli

PMC · DOI: 10.1016/j.radcr.2026.01.098 · Radiology Case Reports · 2026-03-03

## TL;DR

A 35-year-old woman with rare ileocolic varices causing recurrent bleeding was successfully treated with a minimally invasive embolization procedure.

## Contribution

Demonstrates the effectiveness of superselective Onyx embolization for treating rare ileocolic and appendicular varices.

## Key findings

- Multiphase contrast-enhanced CT with venous phase imaging accurately identified ileal varices.
- Superselective embolization using Onyx and glue successfully stopped recurrent bleeding.
- The case highlights the role of endovascular treatment in managing ectopic varices.

## Abstract

Ileocolic and appendicular varices are rare causes of lower gastrointestinal bleeding and are frequently missed on endoscopic evaluation. We present the case of a 35-year-old woman with ulcerative colitis, primary sclerosing cholangitis, and cirrhosis who presented with recurrent hematochezia and severe anemia. Contrast enhanced CT with venous-phase imaging revealed clusters of enhancing ileal varices, and angiography demonstrated ileocolic and appendicular varices with a significant portosystemic shunt draining into the inferior vena cava. Superselective embolization using Onyx followed by glue embolization resulted in complete cessation of bleeding. This case highlights the diagnostic value of multiphase contrast-enhanced CT including venous phase imaging and the effectiveness of minimally invasive endovascular treatment for rare ectopic varices.

## Linked entities

- **Diseases:** ulcerative colitis (MONDO:0005101), primary sclerosing cholangitis (MONDO:0013433), cirrhosis (MONDO:0005155)

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** stenosis (MESH:D003251), bowel ischemia (MESH:D007511), vomiting (MESH:D014839), esophageal varices (MESH:D004932), splenomegaly (MESH:D013163), bleeding (MESH:D006470), extravasation (MESH:D005119), venous abnormalities (MESH:D014647), weakness (MESH:D018908), inflammatory response (MESH:D018746), mesenteric venous abnormality (MESH:D065666), rectal bleeding (MESH:D012002), abdominal pain (MESH:D015746), cirrhosis (MESH:D005355), Ectopic gastrointestinal varices (MESH:D014648), reflux (MESH:D005764), PSC (MESH:D015209), gastrointestinal bleeding (MESH:D006471), ulcerative colitis (MESH:D003093), Chronic inflammatory bowel disease (MESH:D015212), hepatic encephalopathy (MESH:D006501), liver failure (MESH:D017093), allergies (MESH:D004342), Ileocolic and appendicular varices (MESH:D003424), venous shunts (MESH:C562830), metabolic acidosis (MESH:D000138), weight loss (MESH:D015431), thrombosis (MESH:D013927), portal vein thrombosis (MESH:D012170), anemia (MESH:D000740), portal hypertension (MESH:D006975)
- **Chemicals:** octreotide (MESH:D015282), Onyx 18 (MESH:C558446), N-butyl cyanoacrylate (MESH:D004659), mesalazine (MESH:D019804), calcium (MESH:D002118), ursodiol (MESH:D014580), propranolol (MESH:D011433), Lipiodol (MESH:D004998), levothyroxine (MESH:D013974), Onyx (-), rifaximin (MESH:D000078262)
- **Species:** Agaricus bisporus (common mushroom, species) [taxon 5341], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12966855/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12966855/full.md

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Source: https://tomesphere.com/paper/PMC12966855