Primary Ewing′s Sarcoma of the Sinonasal Region: A Rare Clinical Encounter
Ujjwal Sangroula, Prajeeta Bhandari, Ratan Shah, Prajjwol Luitel, Sadmarg Thakur, Monica Shah, Manoj Tamang
TL;DR
This paper reports a rare case of Ewing's sarcoma in the nasal area of an adult, highlighting the challenges in diagnosing such tumors.
Contribution
The novelty lies in presenting a rare adult case of sinonasal Ewing's sarcoma with detailed diagnostic insights.
Findings
Ewing's sarcoma in the sinonasal region is rare, especially in adults.
Accurate diagnosis requires comprehensive histopathological and immunohistochemical analysis.
Abstract
Ewing′s sarcoma (EWS) is a highly aggressive tumor of neuroectodermal origin, rarely occurring in the sinonasal tract, particularly in adults. We report a 27‐year‐old male with long‐standing nasal obstruction, initially misdiagnosed as nasal chondromesenchymal hamartoma. Surgical excision revealed a destructive, vascular sinonasal mass. Histology showed sheets of small round cells within a sclerotic stroma, and immunohistochemistry positivity for CD99, vimentin, cyclin D1, BCL2, and NKX2.2 confirmed EWS. This case underscores the diagnostic difficulty of sinonasal small round cell tumors and the necessity of thorough histopathological and immunohistochemical analysis.
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Taxonomy
TopicsSarcoma Diagnosis and Treatment · Teratomas and Epidermoid Cysts · Bone Tumor Diagnosis and Treatments