# The Gap Is Getting Closer: Trends in Absolute and Relative Black-White HIV Mortality Disparities in the USA (1999–2023)

**Authors:** Ahmed Azzam, Heba Khaled

PMC · DOI: 10.1007/s40615-025-02299-8 · 2025-02-12

## TL;DR

This study examines how the gap in HIV-related deaths between Black and White people in the USA has changed from 1999 to 2023.

## Contribution

The study identifies a significant decline in absolute disparities and a modest reduction in relative disparities in HIV mortality between Black and White populations.

## Key findings

- Absolute HIV mortality disparities decreased by an average of 6.46% annually.
- Relative disparities declined by 1.10% annually, with a notable shift in trend after 2007.
- The 45–54 age group showed the most improvement in both absolute and relative disparities.

## Abstract

This study analyzes trends in HIV-related mortality disparities between Black and White populations in the USA from 1999 to 2023.

CDC WONDER data were utilized to assess absolute disparities, measured as the age-adjusted mortality rate difference, and relative disparities, measured as the age-adjusted mortality rate ratio, in Black-White HIV mortality. Trends were analyzed using Joinpoint regression, with the average annual percentage change (AAPC) serving as a summary measure for the entire period and the annual percentage change (APC) used to evaluate the magnitude of change within specific intervals.

The absolute disparity showed a consistent decline, with an AAPC of − 6.46% (p < 0.001). Similarly, the relative disparity significantly decreased, with an AAPC of − 1.10% (p < 0.001). A detailed analysis of relative disparity revealed a notable inflection point in 2007, marked by an initial increase from 1999 to 2007 (APC 0.96%, p = 0.002), followed by a decline from 2007 to 2023 (APC − 2.12%, p < 0.001). The findings for both Black-White females and males consistently demonstrated reductions in both relative and absolute disparities, aligning with the overall trend. Among age categories, the 45–54 age group showed the greatest improvement in absolute (− 8.11%) and relative (− 2.65%) disparities, while the 25–34 group showed the least, with a slight increase in relative disparity (+ 0.23%, p = 0.66).

This study shows significant progress in reducing absolute Black-White HIV mortality disparities, while the reduction in relative inequalities is more modest, emphasizing the need for continued and strengthened public health efforts.

## Full-text entities

- **Diseases:** HIV (MESH:D015658)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12966235/full.md

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Source: https://tomesphere.com/paper/PMC12966235