# Burnout dimensions and associated risk factors in medical students: A cross-sectional study in Serbia

**Authors:** Irena Ilic, Ivana Zivanovic Macuzic, Milena Ilic, Ana Ravic-Nikolic, Vesna Milicic

PMC · DOI: 10.1371/journal.pone.0344119 · 2026-03-06

## TL;DR

This study explores burnout in Serbian medical students and identifies risk factors like alcohol use and sedative consumption.

## Contribution

The study identifies specific risk factors for burnout dimensions in medical students using a cross-sectional approach in Serbia.

## Key findings

- Higher alcohol consumption increases the risk of all three burnout dimensions in medical students.
- Clinical training level and sedative use are linked to higher emotional exhaustion.
- Positive personal medical history correlates with a higher risk of academic inefficacy.

## Abstract

Burnout syndrome presents a serious problem for medical students in their training and professional career. The aim of this study was to investigate the dimensions of burnout syndrome and associated risk factors among medical students in Serbia.

This was a cross-sectional study. Prevalence of high risk of burnout in medical students was determined following the three-dimensional criteria, based on high levels of emotional exhaustion, cynicism, and low academic efficacy, according to the Maslach Burnout Inventory Student Survey. Odds ratios (OR) with corresponding 95% confidence intervals (95% CI) were determined using multivariate logistic regression analysis.

Risk for high level of all three burnout dimensions (emotional exhaustion, cynicism, and academic inefficacy) was increasing with higher frequency of alcohol consumption (p for trend = 0.008, p = 0.030, p = 0.040, respectively) in medical students. Risk for high level of emotional exhaustion was associated with clinical training level of studies (OR = 1.82, 95% CI = 1.38–2.80, p = .007) and use of sedatives (OR = 3.08, 95% CI = 1.29–7.38, p = 0.011). Length of study >6 years and use of sedatives were associated with high level of cynicism in medical students (OR = 1.98, 95% CI = 1.08–3.62, p = 0.027; OR = 3.19, 95% CI = 1.31–7.75, p = 0.010, respectively). Higher grade point average (>8) was most common in medical students with lower risk of academic inefficacy (OR = 0.65, 95%CI = 0.44–0.95, p = 0.026). Positive personal medical history (presence of any chronic disease) was frequently reported in medical students who had a high risk of academic inefficacy (OR = 2.45, 95% CI = 1.30–4.61, p = 0.006).

Some characteristics of medical students were associated with high risk of burnout, indicating the need for psychological support aimed at providing appropriate help and assistance to medical students.

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), infections (MESH:D007239), Burnout (MESH:D002055), chronic diseases (MESH:D002908), depression (MESH:D003866), emotional exhaustion (MESH:D006359), excessive alcohol consumption (MESH:D000435), alcohol and drug abuse (MESH:D019966), anxiety (MESH:D001007), alcohol abuse/dependence (MESH:D000437), sleep disturbances (MESH:D012893), psychological distress (MESH:D012128), suicidal ideation (MESH:D001072)
- **Chemicals:** CY (-), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606], Meleagris gallopavo (common turkey, species) [taxon 9103]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12965603/full.md

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Source: https://tomesphere.com/paper/PMC12965603