# Editorial Note: Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status

PMC · DOI: 10.1371/journal.pone.0344076 · 2026-03-06

## Full-text entities

- **Genes:** TP53 (tumor protein p53) [NCBI Gene 7157] {aka BCC7, BMFS5, LFS1, P53, TRP53}, POTEF (POTE ankyrin domain family member F) [NCBI Gene 728378] {aka A26C1B, POTE2alpha, POTEACTIN}
- **Diseases:** liver cancer (MESH:D006528), cancer (MESH:D009369)
- **Chemicals:** 4-methylthiobutyl isothiocyanate (MESH:C587983)
- **Cell lines:** Huh7 — Homo sapiens (Human), Adult hepatocellular carcinoma, Cancer cell line (CVCL_0336)

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Source: https://tomesphere.com/paper/PMC12965597