# Infectious retinitis associated with JAK inhibitors: the ongoing duality of JAK inhibitors

## TL;DR

This paper highlights the risk of vision-threatening eye infections caused by JAK inhibitors, urging prompt specialist care when symptoms arise.

## Contribution

The paper adds new clinical cases and emphasizes the need for awareness of retinal complications linked to JAK inhibitors.

## Key findings

- Six cases of cytomegalovirus retinitis linked to JAK inhibitors have been reported.
- One case each of toxoplasma retinitis and herpetic scleritis was also associated with JAK inhibitors.
- Acute vision loss and floaters are warning signs requiring urgent referral to a retina specialist.

## Abstract

To discuss the recent evidence that Janus kinase (JAK) inhibitors can cause viral retinitis.

A commentary on the case report in this issue and a review of cases in the literature.

A total of 6 cases have now been reported of cytomegalovirus retinitis associated with Jak inhibitors. Additionally, there was a case of bilateral toxoplasma retinitis and a case of herpetic scleritis.

It is important to be aware of the potential blinding complications associated with JAK inhibitors and if the patient complains of acute vision loss and/or floaters, the patient should be emergently referred to a retina specialist.