Safety assessment of the substance (2E,2′E)‐2,4,8,10‐tetraoxaspiro[5.5]undecane‐3,9‐diylbis(2‐methylpropane‐2,1‐diyl) bis(2‐cyano‐3‐(3,4‐dimethoxyphenyl)acrylate for use in plastic food contact materials
Claude Lambré, Riccardo Crebelli, Maria da Silva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Ronan Cariou, Laurence Castle, Emma Di Consiglio, Roland Franz, Eric Barthélémy
TL;DR
This study evaluates the safety of a chemical used in plastic food packaging and concludes it is safe under specific conditions.
Contribution
The study provides a safety assessment of a new chemical additive in food contact materials with defined usage limits and migration thresholds.
Findings
The substance's migration into food simulants was up to 33 μg/kg, with impurities generally below detection limits.
Genotoxicity studies showed no safety concerns for the substance or its impurities.
The substance is safe for use in PET food contact materials under specified conditions and migration limits.
Abstract
The EFSA Panel on Food Contact Materials (FCM) assessed the safety of (2E,2′E)‐2,4,8,10‐tetraoxaspiro[5.5]undecane‐3,9‐diylbis(2‐methylpropane‐2,1‐diyl) bis(2‐cyano‐3‐(3,4‐dimethoxyphenyl)acrylate, which is intended to be used as an additive at up to 0.75% w/w in polyethylene terephthalate (PET) single‐use articles for contact with all types of food, for long‐term storage at room temperature including hot fill and/or heating up to 100°C for a maximum of 2 h. Migration tests were carried out into the food simulants 3% acetic acid, 10% ethanol and olive oil, using PET samples containing the substance at the maximum intended level. The specific migration of the substance was up to 33 μg/kg food. The individual migration of its impurities was generally below the limits of quantification or not detected at the limits of detection, both in the few μg/kg food range, except for…
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Taxonomy
TopicsOccupational exposure and asthma · Agricultural safety and regulations · Carcinogens and Genotoxicity Assessment