# Editorial: Neurobiological basis of substance use disorders: new findings and perspectives

**Authors:** Cristiane Aparecida Favoretto, Cássio Morais Loss, Valentina Vozella, Fábio Cardoso Cruz

PMC · DOI: 10.3389/fnins.2025.1744297 · Frontiers in Neuroscience · 2026-02-20

## Full-text entities

- **Genes:** Fos (Fos proto-oncogene, AP-1 transcription factor subunit) [NCBI Gene 14281] {aka D12Rfj1, c-fos, cFos}, Adcyap1 (adenylate cyclase activating polypeptide 1) [NCBI Gene 11516] {aka PACAP}, Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) [NCBI Gene 15558] {aka 5-HT-2, 5-HT-2A, E030013E04, Htr-2, Htr2}, Cnr1 (cannabinoid receptor 1) [NCBI Gene 12801] {aka CB-R, CB1, CB1A, CB1B, CB1R}, Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) [NCBI Gene 15560] {aka 5-HT-1C, 5-HT-2C, 5-HT1C, 5-HT2C, 5-HT2cR, 5-HTR2C}, Drd1 (dopamine receptor D1) [NCBI Gene 13488] {aka C030036C15Rik, Drd-1, Drd1a, Gpcr15}
- **Diseases:** depression (MESH:D003866), BD (MESH:D001714), PTSD (MESH:D013313), CL (MESH:D002971), AUD (MESH:D000437), neuropsychiatric disorders (MESH:D001523), SUDs (MESH:D019966), neuroinflammation (MESH:D000090862), schizophrenia (MESH:D012559), anxiety (MESH:D001007), CF (MESH:D003550)
- **Chemicals:** cannabinoid (MESH:D002186), ethanol (MESH:D000431), CIE (-), cocaine (MESH:D003042), nicotine (MESH:D009538), corticosterone (MESH:D003345)
- **Species:** Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12964197/full.md

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Source: https://tomesphere.com/paper/PMC12964197