# The State of the Art in Septoplasty: A Review of the Latest Achievements

**Authors:** Masoud Janipour, Fatemeh Rezaei-Tazangi

PMC · DOI: 10.1155/bmri/7066464 · BioMed Research International · 2026-03-06

## TL;DR

This review discusses recent advancements in septoplasty, a surgery to correct nasal septum deviations, focusing on improving outcomes and reducing complications.

## Contribution

The paper provides a critical appraisal of the latest strategies and evidence in septoplasty aimed at enhancing effectiveness and minimizing risks.

## Key findings

- Recent strategies focus on improving pain management and restoring olfactory function after septoplasty.
- New techniques aim to promote nasal mucosa healing and close septal perforations post-surgery.
- The review contrasts high-level evidence with preliminary findings from novel approaches.

## Abstract

The deviated nasal septum is the most common cause of nasal airway obstruction, frequently diagnosed by otolaryngologists in clinical practice. Reports displayed that this condition affects 70%–80% of the population. The etiology of this upper airway problem is mainly related to intrinsic deformity or quadrangular cartilage dislocation from its bony borders, which can finally confer different disorders, such as breathing problems, sinus infections, snoring, headaches, exacerbating sleep apnea, and sleep disturbances. One of the most common methods for correcting a deviated nasal septum is septoplasty. However, this procedure still requires significant improvements to enhance its effectiveness and reduce the risk of surgery‐related complications, particularly nasal septal perforation and the recurrence of deviation in adolescents and adults. In recent years, numerous strategies have been proposed to enhance septoplasty outcomes and reduce surgery‐related complications. Many of these approaches focus on improving pain management, restoring olfactory function, alleviating symptoms, and enhancing clinical nasal outcomes. Additionally, they are aimed at promoting healing of the nasal mucosa and close septal perforations following surgery. This narrative review critically appraises the latest advancements in septoplasty, contrasting high‐level evidence from large multicenter trials with promising but preliminary findings from novel techniques aimed at enhancing outcomes and reducing complications.

## Linked entities

- **Diseases:** sleep apnea (MONDO:0005296)

## Full-text entities

- **Diseases:** septicemia (MESH:D018805), snoring (MESH:D012913), rhinosinusitis (MESH:D000092562), toxic shock syndrome (MESH:D012772), sleep apnea (MESH:D012891), Nasal Obstruction Symptom (MESH:D015508), pneumocephalus (MESH:D011007), Perforations (MESH:D057112), septum (MESH:D000093665), cardiac and ocular complications (MESH:D006331), allergies (MESH:D004342), rhinitis medicamentosa (MESH:D012220), obstructive sleep apnea (MESH:D020181), deformity (MESH:D009140), mucosal swelling (MESH:D052016), septal defects (MESH:D006343), hyposmia (MESH:D000086582), nasal tip ptosis (MESH:D060725), congestion (MESH:D002311), infection (MESH:D007239), nasal congestion (MESH:D009668), chronic allergic rhinitis (MESH:D065631), adhesions (MESH:D000267), Cavity (MESH:D003731), anosmia (MESH:D000857), quadrangular cartilage dislocation (MESH:D002357), facial pains (MESH:D005157), epistaxis (MESH:D004844), NSP (MESH:D061270), autoimmune disease (MESH:D001327), septal perforation (MESH:D018658), Hemorrhage (MESH:D006470), smoking (MESH:D015208), CSF) leak (MESH:D065634), deviated (MESH:D010262), meningitis (MESH:D008580), edema (MESH:D004487), Sluder's syndrome (MESH:D005359), malignancy (MESH:D009369), sense (MESH:D020886), sleep disturbances (MESH:D012893), pain (MESH:D010146), cerebrospinal fluid ( (MESH:D002559), sinus infections (MESH:D012852), trauma (MESH:D014947), vasculitis (MESH:D014657), saddle (MESH:C536025), headaches (MESH:D006261), inflammation (MESH:D007249), abscess (MESH:D000038), NSD (MESH:D029461), hematoma (MESH:D006406)
- **Chemicals:** Xylometazoline hydrochloride (MESH:C009695), Cocaine (MESH:D003042), PPE (-), Silicone (MESH:D012828), mometasone furoate (MESH:D000068656), saccharin (MESH:D012439)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12964075/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12964075/full.md

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Source: https://tomesphere.com/paper/PMC12964075