# Prognostic Value of Selective Nerve Root Blocks Prior to Pulsed Radiofrequency in the Treatment of Patients With Chronic Radicular Pain: A Systematic Review

## TL;DR

This review examines if a positive response to nerve blocks can predict successful treatment outcomes for chronic nerve pain using radiofrequency therapy.

## Contribution

The study systematically evaluates the prognostic value of selective nerve root blocks for pulsed radiofrequency treatment in chronic radicular pain.

## Key findings

- A positive SNRB response was associated with higher treatment success likelihood at 6 weeks.
- Baseline disability, age over 55, and SNRB response predicted success at 6 months with moderate accuracy.
- Only one study met criteria, highlighting a significant gap in high-quality evidence on this topic.

## Abstract

Selective nerve root blocks (SNRBs) are frequently used in clinical algorithms for managing chronic radicular pain. However, their prognostic value in identifying patients likely to benefit from pulsed radiofrequency (PRF) treatment remains uncertain.

This systematic review evaluates whether a positive response to an SNRB predicts improved clinical outcomes following PRF in patients with chronic radicular pain.

A systematic search was conducted in PubMed, Embase, and Cochrane databases, along with reference lists of relevant articles. Eligible studies included patients with chronic radicular pain and assessed the prognostic role of SNRBs administered prior to PRF. Risk of bias was assessed using the ROBINS‐I V2 tool.

Only one prospective observational study met inclusion criteria. In patients with chronic lumbosacral radicular pain, a positive SNRB response was associated with a higher likelihood of treatment success at 6‐week follow‐up (odds ratio: 3.26; 95% CI: 0.97–11.00; p = 0.06). Multivariate analysis identified limited baseline disability, age > 55 years, and a positive SNRB response as predictors of success at 6 months, with an area under the receiver operating characteristic curve of 0.73.

This review identified a lack of published studies—aside from one prospective observational study—examining the prognostic value of SNRBs in the context of PRF for chronic radicular pain. The findings underscore not only a lack of high‐quality evidence but a broader gap in the literature. Further robust research is warranted to clarify the clinical utility of SNRBs in guiding PRF treatment decisions.