# Small but mighty: Rhabdomyoblastic melanoma

**Authors:** Surya A. Veerabagu, Kimberly Artounian, Shelly Stepenaskie, Brian Hinds, Andrew Matsumoto

PMC · DOI: 10.1016/j.jdcr.2026.01.045 · JAAD Case Reports · 2026-02-03

## Full-text entities

- **Genes:** MITF (melanocyte inducing transcription factor) [NCBI Gene 4286] {aka CMM8, COMMAD, MI, MITF-A, WS2, WS2A}, S100A1 (S100 calcium binding protein A1) [NCBI Gene 6271] {aka S100, S100-alpha, S100A}, SOX10 (SRY-box transcription factor 10) [NCBI Gene 6663] {aka DOM, PCWH, SOX-10, WS2E, WS4, WS4C}, MYOD1 (myogenic differentiation 1) [NCBI Gene 4654] {aka CMYO17, CMYP17, MYF3, MYOD, MYODRIF, PUM}, MYOG (myogenin) [NCBI Gene 4656] {aka MYF4, bHLHc3, myf-4}, PDCD1 (programmed cell death 1) [NCBI Gene 5133] {aka ADMIO4, AIMTBS, CD279, PD-1, PD1, SLEB2}, DES (desmin) [NCBI Gene 1674] {aka CDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R}, PRAME (PRAME nuclear receptor transcriptional regulator) [NCBI Gene 23532] {aka CT130, MAPE, OIP-4, OIP4}, MLANA (melan-A) [NCBI Gene 2315] {aka MART-1, MART1}, BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}
- **Diseases:** death (MESH:D003643), cutaneous disease (MESH:D004194), Rhabdomyoblastic melanoma (MESH:D008545), lentigo maligna melanoma (MESH:D018327), melanoma metastases (MESH:D009362), desmoplastic and lentigo melanoma (MESH:D007911), ulcerated (MESH:D014456), tumor (MESH:D009369), Primary cutaneous melanoma (MESH:C562393), pleomorphic (MESH:D008228), lymphadenopathy (MESH:D008206), Dermal tumor (MESH:D057091), nonmelanoma skin cancers (MESH:D012878)
- **Chemicals:** dacarbazine (MESH:D003606), pembrolizumab (MESH:C582435)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** V600E

## Full text

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## Figures

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## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12963897/full.md

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Source: https://tomesphere.com/paper/PMC12963897