# The Relative Understanding of Stigma About Health (RUSH) Study: The Role of Controllability and Knowledge in Explaining Condition-Specific Variability

**Authors:** Charlotte S. Zell, Steven R. Thorp, Kenneth J. Thompson

PMC · DOI: 10.1007/s10597-025-01544-y · Community Mental Health Journal · 2025-10-28

## TL;DR

This study explores how perceptions of controllability and knowledge affect stigma toward various health conditions in the U.S.

## Contribution

The study introduces the RUSH-I, a new tool to measure stigma across 36 health conditions and behaviors.

## Key findings

- Stigma is higher for conditions perceived as more controllable and less understood.
- Mental health conditions are generally more stigmatized than physical ones, except for obesity, which is most stigmatized.
- At the individual level, greater knowledge is associated with higher perceived stigma.

## Abstract

Members of the U.S. public report negative stereotypes, prejudice, and discrimination towards individuals with a variety of health issues. The present study aimed to identify which health conditions and behaviors are most stigmatized and shed light on the factors that drive variation in stigma. A large, nationally representative sample of U.S. adults (N = 1,096) provided valid online survey responses to the Relative Understanding of Stigma about Health Index (RUSH-I), a novel instrument that assesses perceptions of controllability, knowledge, and perceptions of public stigma for 36 different conditions and behaviors. We hypothesized a positive relationship between controllability and stigma and an inverse relationship between knowledge and stigma. As hypothesized, stigma was substantially higher among conditions and behaviors that participants perceived as more controllable and about which they reported less knowledge. Controllability and knowledge accounted for over two-thirds of the variance in stigma across health issues. At the individual level, however, knowledge was positively related to stigma: Participants who reported more knowledge about a health condition or behavior tended to perceive greater stigma associated with it. Results showed that mental health conditions were generally more stigmatized than physical health conditions. Obesity was a notable exception, ranking as the most stigmatized health condition overall. These findings may help guide public health messaging, especially which conditions should be targets for stigma intervention. The findings also highlight important areas for further research, including elaborating the relationship between knowledge and stigma at both the individual and condition level.

## Full-text entities

- **Diseases:** Obesity (MESH:D009765)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12963089/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12963089/full.md

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Source: https://tomesphere.com/paper/PMC12963089