# Diagnostic Challenges and Surgical Management of Ovarian Hydatid Cyst: A Case Report From an Endemic Region and Literature Review

**Authors:** Fatemeh Asadi Kohbad, Razieh Akbari, Maryam Forouzin, Fatemeh Nili, Leila Asadi, Marjan Ghaemi

PMC · DOI: 10.1002/ccr3.72113 · Clinical Case Reports · 2026-03-05

## TL;DR

This case report highlights the diagnostic and surgical challenges of ovarian hydatid cysts in an endemic region, emphasizing the importance of accurate diagnosis and treatment.

## Contribution

The paper contributes a detailed case report and literature review on the rare condition of ovarian hydatid cysts, emphasizing diagnostic and management strategies in endemic regions.

## Key findings

- Ovarian hydatid cysts can mimic ovarian neoplasms, requiring a high index of suspicion for accurate diagnosis.
- Surgical management combined with anthelmintic therapy is effective in treating ovarian hydatid cysts.
- Ultrasound and CT imaging, along with histopathological evaluation, are crucial for diagnosis.

## Abstract

Ovarian hydatid cysts are an infrequent presentation of the zoonotic condition caused by Echinococcus granulosus tapeworms. These cysts can easily be mistaken for benign or malignant ovarian neoplasms, posing a diagnostic challenge. This case report describes managing a case of ovarian hydatid cyst in an endemic region. A 50‐year‐old woman, who had previously undergone surgery for a liver hydatid cyst, presented with abdominal pain and amenorrhea. Upon further investigations, it was revealed that a multilocular cystic lesion was in her left ovary through ultrasonography and computed tomography. Tumor markers were within normal limits. Intraoperative evaluation confirmed the diagnosis of a hydatid cyst, leading to a decision for a total abdominal hysterectomy with bilateral salpingo‐oophorectomy. The surgery was performed to remove the cyst safely. Following the procedure, the patient received anthelmintic therapy with albendazole. The outpatient follow‐up was focused on monitoring the patient's recovery and response to treatment. In conclusion, ovarian hydatid cysts are a rare entity that can mimic ovarian neoplasms, particularly in endemic regions. A high index of suspicion, along with appropriate imaging and histopathological examination, is crucial for accurate preoperative diagnosis. Surgical management, combined with perioperative anthelmintic therapy, is the mainstay of treatment to minimize the risk of recurrence and complications. Clinicians should be vigilant in considering hydatid disease as a differential diagnosis for cystic ovarian masses in endemic regions, even in the absence of a known history of the disease.

Ovarian hydatid cysts, rare yet resembling ovarian neoplasms, require careful differential diagnosis in endemic areas. Preoperative suspicion, imaging, and histopathology are essential. Surgical treatment, coupled with perioperative anthelmintic therapy, remains the cornerstone to prevent recurrence and complications. Clinicians must consider hydatid disease, even without a prior history, when evaluating cystic ovarian masses.

Ultrasound imaging demonstrating a multilocular cystic lesion in the left ovary, characterized by internal echogenic septa, prompting further evaluation to assess potential underlying conditions.

## Linked entities

- **Chemicals:** albendazole (PubChem CID 2082)

## Full-text entities

- **Genes:** MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}
- **Diseases:** fibroma (MESH:D005350), parasitic disease (MESH:D010272), ovarian neoplasms (MESH:D010051), uterine-vaginal adhesions (MESH:D014627), uterine prolapse (MESH:D014596), cystic ovarian masses (MESH:D010049), Cysts (MESH:D003560), infectious disease (MESH:D003141), neutropenia (MESH:D009503), cystocele (MESH:D052858), infection (MESH:D007239), leukocytosis (MESH:D007964), hepatic hydatid cyst (MESH:D004444), multilocular cysts (MESH:C536591), lymphadenopathy (MESH:D008206), alopecia (MESH:D000505), nausea (MESH:D009325), jaundice (MESH:D007565), adnexal (MESH:D000292), rectocele (MESH:D020047), amenorrhea (MESH:D000568), vomiting (MESH:D014839), helminthic disease (MESH:D004194), Hydatid Cyst (MESH:D004443), condition (MESH:D020763), Ovarian Hydatid Cyst (MESH:D010048), inflammatory (MESH:D007249), Pain (MESH:D010146), NILM (MESH:D000081483), cystic (MESH:D018297), rupture (MESH:D012421), atrophic uterus (MESH:D014594), Tumor (MESH:D009369), adnexal lesion (MESH:D000291), abdominal pain (MESH:D015746)
- **Chemicals:** ABZ (MESH:D015766), anthelmintic drugs (-), H&amp;E (MESH:D006371), hematoxylin (MESH:D006416), benzimidazole (MESH:C031000), chlorhexidine (MESH:D002710), rosin (MESH:C013893), mebendazole (MESH:D008463)
- **Species:** Cestoda (tapeworms, class) [taxon 6199], Echinococcus granulosus (species) [taxon 6210], Homo sapiens (human, species) [taxon 9606], Echinococcus multilocularis (species) [taxon 6211]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12962876/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12962876/full.md

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Source: https://tomesphere.com/paper/PMC12962876