# Effects of standardized ileal digestible lysine:crude protein ratio and the use of non-protein nitrogen on growth performance of 11- to 25-kg pigs

## TL;DR

This study finds that feeding pigs with a high lysine-to-protein ratio above 6.5% reduces feed efficiency, but adding nitrogen sources can help.

## Contribution

The study identifies optimal lysine-to-protein ratios and the benefits of adding nitrogen sources in low-protein pig diets.

## Key findings

- A SID Lys:CP ratio above 6.5% decreases gain:feed ratio in pigs.
- Adding diammonium phosphate or glycine improves feed efficiency in high lysine diets.
- Interactions between lysine levels and feed ingredients like DDGS affect growth performance.

## Abstract

Three experiments were conducted to determine if nitrogen is a limiting factor for growth performance when feeding low protein, amino acid (AA) fortified diets and determine the effects of standardized ileal digestible lysine to crude protein (SID Lys:CP) ratio on growth performance of 11- to 25-kg pigs. In Exp. 1,981 pigs ([Fast Large White × PIC L02] × PIC 800; initially 10.3 ± 0.19 kg) were used in a 21-d study. Diets were corn-soybean meal-based consisting of: 1) a low level of feed-grade AA with a SID Lys:CP ratio of 6.0%; 2) a moderate level of feed-grade AA with a SID Lys:CP ratio of 6.5%; 3) a high level of feed-grade AA with a SID Lys:CP ratio of 7.0%; 4) diet 3 with added diammonium phosphate (DAP) added to achieve a SID Lys:CP ratio of 6.5%; and 5) diet 3 with L-Gly added to achieve a SID Lys:CP ratio of 6.5%. Average daily gain (ADG) was unaffected by dietary treatment but gain:feed ratio (G:F) decreased (linear, P = 0.002; quadratic, P = 0.054) as SID Lys:CP ratio exceeded 6.5%. Adding DAP or L-Gly to the high feed-grade AA diet increased (P ≤ 0.003) G:F compared to pigs fed the high feed-grade AA diet. In Exp. 2, 4,167 pigs (337 × 1050, PIC; initially 13.0 ± 0.27 kg) were used in a 14-d study. Diets were corn-soybean meal-based, and treatments arranged in a 2 × 5 factorial with main effects of SID Lys (1.15 or 1.30%) and SID Lys:CP ratio (6.00, 6.22, 6.46, 6.72, and 7.00%). Overall ADG was unaffected by dietary treatment; however, a SID Lys:CP × SID Lys interaction was observed for G:F (linear, P = 0.012) where increasing SID Lys:CP ratio decreased (linear, P < 0.001) G:F at both SID Lys levels with a more pronounced effect in diets formulated to 1.15% SID Lys. Lastly, Exp. 3 used 5,059 pigs (PIC 800 × Camborough and DNA 600 × 241; initially 11.0 ± 0.90 kg) in an 18-d trial. Treatment diets were arranged in a 2 × 6 factorial with main effects of dried distillers grains with solubles (DDGS; 0 or 15%) and SID Lys:CP ratio (6.01, 6.22, 6.45, 6.70, 6.97, and 7.26%). Overall, ADG was unaffected by dietary treatment, but a SID Lys:CP × DDGS interaction was observed (linear, P < 0.001) where G:F increased then decreased (quadratic, P < 0.001) in diets without DDGS, whereas in the diets with DDGS, G:F decreased (quadratic, P ≤ 0.002) as SID Lys:CP ratio increased above 6.45%. In summary, a SID Lys:CP ratio greater than approximately 6.5% decreased G:F, but adding a protein or non-protein nitrogen source to low protein diets formulated above this ratio improves G:F.

Feeding a standardized ileal digestible lysine:crude protein ratio greater than 6.5% negatively affects feed efficiency in 11- to 25-kg pigs.