# “Miss, I want itchy medicine”: Understanding what, why, and how antibiotics are used in Central Java province, Indonesia through the drug bag method

**Authors:** Soe Yu Naing, Mira L. Schneiders, Dhini Ningrum, Tri Nurdianti, Juliëtte Severin, Koen Peeters Grietens, Jaap A. Wagenaar, Anis Karuniawati

PMC · DOI: 10.1371/journal.pgph.0005933 · 2026-03-05

## TL;DR

This study explores how and why people in Central Java, Indonesia use antibiotics, finding that easy access and low knowledge drive self-medication practices.

## Contribution

The study introduces the drug bag method to investigate community antibiotic use, revealing social, economic, and cultural drivers in Indonesia.

## Key findings

- Amoxicillin and tetracycline are the most commonly used and recognized antibiotics in the region.
- Self-medication is driven by convenience, cost, and easy access to antibiotics in pharmacies and local shops.
- Practices like early treatment cessation and sharing antibiotics among family are common.

## Abstract

Antibiotic use is shaped by access, knowledge, norms, and practices, yet remains poorly understood in many community settings worldwide. To address these gaps, we investigated community antibiotic use in six villages across Sukoharjo, Karanganyar, and Klaten districts of Central Java province in Indonesia. This study focused on three key questions: (i) which antibiotics are accessible in community settings; (ii) how do community members recognize and understand these antibiotics; and (iii) what social, economic, cultural, and contextual factors drive antibiotic use. Between April and May 2024, 36 drug bag interviews, in which locally available antibiotics were purchased, compiled, and used in household pile-sorting activities, were conducted with community members. Complementary ethnographic fieldwork included simulated patient visits, informal conversations, and participant observations in community settings and at local pharmacies and shops (Warungs). This study found that knowledge of antibiotics and Indonesian medicine labels was generally low, while access to antibiotics without prescription, particularly from pharmacies and Warungs, was high. Access antibiotics, such as amoxicillin and tetracycline, were the most commonly used and recognized, while Watch antibiotics, including aminoglycosides, were also popular for self-medication, especially in topical forms. Common reasons for self-medication included convenience, ease of access, and lower cost. Practices such as stopping treatment early, repurposing antibiotics, and sharing them among family members were commonly adopted. This study identified multiple intersecting factors influencing antibiotic use in community settings. The findings highlight that effective antibiotic stewardship requires not only policies to restrict non-prescription sales but also interventions that address the social, economic, and cultural drivers of self-medication.

## Linked entities

- **Chemicals:** amoxicillin (PubChem CID 33613), tetracycline (PubChem CID 54675776)

## Full-text entities

- **Genes:** SYNM (synemin) [NCBI Gene 23336] {aka DMN, SYN}
- **Diseases:** AMR (MESH:D060467), diabetes (MESH:D003920), infected (MESH:D007239), cold (MESH:D000067390), ulcer (MESH:D014456), UTIs (MESH:D014552), cough (MESH:D003371), wound infections (MESH:D014946), nerve disorders (MESH:D005155), throat inflammation (MESH:D007249), wounds (MESH:D014947), tendon damage (MESH:D013708), skin irritation (MESH:D012871), viral infections (MESH:D014777), eczema (MESH:D004485), sore throat (MESH:D010612), hypertension (MESH:D006973), Tetra (MESH:C535269), food-borne infections (MESH:D005517), fever (MESH:D005334), burns (MESH:D002056), itching (MESH:D011537), bacterial infections (MESH:D001424), Non-communicable diseases (MESH:D000073296), diarrhea (MESH:D003967)
- **Chemicals:** Pipemidic acid (MESH:D010876), ciprofloxacin (MESH:D002939), ibuprofen (MESH:D007052), Betason-N (-), nitrofurantoin (MESH:D009582), Tetra (MESH:D013752), fosfomycin (MESH:D005578), paracetamol (MESH:D000082), aminoglycoside (MESH:D000617), Neomycin (MESH:D009355), Amoxicillin (MESH:D000658), steroids (MESH:D013256), methylprednisolone (MESH:D008775), cefixime (MESH:D020682), cefadroxil (MESH:D002434), cotrimoxazole (MESH:D015662)
- **Species:** Homo sapiens (human, species) [taxon 9606], Gallus gallus (bantam, species) [taxon 9031], Capra hircus (domestic goat, species) [taxon 9925], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Bos taurus (bovine, species) [taxon 9913]

## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12962538/full.md

---
Source: https://tomesphere.com/paper/PMC12962538