# Revisiting the associations between cooking oils and survival among older people in China: A nationwide, community-based, prospective cohort study

**Authors:** Kexin Wang, Chao Ban, Liming Zhao, Haiyan Ruan, Ziqiong Wang, Yi Zheng, Sen He

PMC · DOI: 10.1371/journal.pone.0344282 · 2026-03-05

## TL;DR

This study found that using lard for cooking is linked to better survival from cardiovascular disease compared to vegetable oils in older Chinese adults.

## Contribution

The study provides new evidence on the differential survival outcomes associated with cooking oil types in older Chinese populations.

## Key findings

- Cooking with lard was associated with higher cardiovascular disease-specific survival compared to vegetable oils.
- No significant differences in overall survival or non-CVD-specific survival were found between lard and vegetable oils.
- Multivariate models confirmed lard's significant association with longer CVD-specific survival.

## Abstract

The study aimed to investigate the associations between cooking oils and survival outcomes in a nationwide, community-based, prospective cohort study of older adults in China.

A total of 5372 older participants (median age: 85.0, inter-quartile range [IQR] age: 77.0–93.0; male: 46.1%) from the 2014 wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2014 were included, with follow-up until 2018. The exposure was cooking oils, including vegetable oils and lard, and outcomes were overall survival (OS) and disease-specific survival (i.e., cardiovascular disease [CVD]-specific survival and non-CVD-specific survival). Accelerated failure time (AFT) models were used to analyze the associations between cooking oils and study outcomes.

During a median follow-up of 3.5 years (IQR: 2.4–4.2 years), 2064 (38.4%) deaths were recorded, including 433 CVD deaths, 1229 non-CVD deaths, and 402 deaths with unknown causes. Kaplan-Meier analysis revealed cooking with lard was associated a higher CVD-specific survival probability than vegetable oils (93.9% vs. 88.2%, log-rank p < 0.001); however, there were no significant differences in OS and non-CVD-specific survival between the two groups (log-rank p = 0.076 and 0.210, respectively). Furthermore, multivariate AFT models indicated cooking with lard was significantly associated with a longer CVD-specific survival compared to vegetable oils (time ratio [TR]=1.44, 95% confidence interval [CI]: 1.08–1.91), and was not associated with OS and non-CVD-specific survival, with adjusted TRs of 1.06 (95% CI: 0.95–1.18) for OS and 1.08 (95% CI: 0.93–1.26) for non-CVD-specific survival, respectively.

Cooking with lard was associated with significantly longer CVD- specific survival compared to vegetable oils among older adults in China.

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** Central obesity (MESH:D056128), hepatic glucose intolerance (MESH:D018149), obesity (MESH:D009765), CLHLS (MESH:C562377), Overweight (MESH:D050177), stroke (MESH:D020521), heart disease (MESH:D006331), cardiovascular disease (MESH:D002318), diabetes (MESH:D003920), Cancer (MESH:D009369), cerebrovascular disease (MESH:D002561), ADL disability (MESH:D020773), inflammation (MESH:D007249), prostate cancer (MESH:D011471), hypertension (MESH:D006973), respiratory disease (MESH:D012140), death (MESH:D003643)
- **Chemicals:** oleic acid (MESH:D019301), cholesterol (MESH:D002784), safflower oil (MESH:D012450), vegetable oil (MESH:D010938), linolenic acid (MESH:D017962), gingili oils (MESH:D012715), corn oil (MESH:D003314), vitamin K 2 (MESH:D024482), carbohydrates (MESH:D002241), canola (MESH:D000074262), oil (MESH:D009821), SFA (MESH:D005227), Cooking oils (-), olive oil (MESH:D000069463), lard (MESH:C029310), linoleic acid (MESH:D019787), UFA (MESH:D005231)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12962501/full.md

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Source: https://tomesphere.com/paper/PMC12962501