# A missed opportunity: faith leaders and the HPV vaccination effort in Addis Ababa, Ethiopia

**Authors:** Wosene Berhanu, Simon Yigremachew, Claudia Hanson, Helena Avermark, Adamu Addissie, Sibylle Herzig van Wees

PMC · DOI: 10.1080/16549716.2026.2635822 · 2026-03-04

## TL;DR

The study explores how faith leaders in Ethiopia could help promote HPV vaccination but face challenges like mistrust and inconsistent information.

## Contribution

The study highlights the untapped potential of faith leaders in promoting HPV vaccination through culturally tailored communication.

## Key findings

- Faith leaders face mistrust of Western vaccine aid and inconsistent information.
- Culturally relevant materials can help faith leaders become effective HPV vaccination advocates.
- Engaging faith leaders can strengthen trust and support cervical cancer elimination goals.

## Abstract

Cervical cancer causes morbidity and mortality among women worldwide, particularly in low- and middle-income countries (LMICs). Human Papillomavirus (HPV) vaccine is crucial for cervical cancer prevention, yet the vaccination rates remain suboptimal in Ethiopia. Studies identified cultural and religious factors as key barriers. While evidence suggests that faith leaders can effectively promote public health interventions, their potential role in HPV vaccination efforts has largely been overlooked and remains inadequately understood.

This study aimed to explore the perspectives of faith leaders in Addis Ababa to identify factors influencing HPV vaccination among girls.

This study employed qualitative methods, using in-depth interviews with purposively selected faith leaders. The faith leaders employed by the Inter-Religious Counsel of Ethiopia (IRCE) were excluded. A total of 13 faith leaders participated in the interviews. The 5C framework informed the data collection tool, and data analysis was conducted using inductive reflexive thematic analysis (RTA).

Faith leaders are navigating between modern medicine and their religious beliefs, face distrust of Western vaccine aid intentions and local HPV vaccine providers, and receive fragmented or inconsistent information. These challenges make it difficult for them to act as champions for the vaccination, but with clear, well-organized information, there is an opportunity to involve them more effectively.

Faith leaders face several challenges that limit their role in promoting HPV vaccination. This study recommends providing clear, culturally relevant materials and communication strategies to support faith leaders and their communities. With these tools, faith leaders have the opportunity to engage and become effective advocates for the elimination of cervical cancer.

This study identified faith leaders’ perspectives and the barriers that hinder their involvement as advocates for Human Papillomavirus vaccination in Ethiopia, including religious influence, mistrust of Western actors, and gaps resulting from inconsistent information.

The study provides new knowledge by emphasizing the untapped potential of faith leaders in promoting vaccine uptake and underscoring the importance of engaging them through structured, culturally tailored communication.

This result supports strategies to integrate faith leaders into HPV vaccination efforts, strengthening trust and their active contribution towards advancing national cervical cancer elimination goals.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), abortion (MESH:D000026), infertility (MESH:D007246), death (MESH:D003643), breast cancer (MESH:D001943), cancer (MESH:D009369), Cervical cancer (MESH:D002583)
- **Chemicals:** Holy water (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human papillomavirus (species) [taxon 10566]

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Source: https://tomesphere.com/paper/PMC12961706