# Neurilemmoma Masquerading a Dermoid Cyst at the Inferior Mandibular Margin: An Unusual Clinical Occurrence

**Authors:** Bibek Kattel, Akunchan Shrestha, Siddhartha Rai, Niroj Khanal, Shashi Keshwar, Mehul Rajesh Jaisani

PMC · DOI: 10.1155/crid/9976255 · 2026-03-05

## TL;DR

A rare case where a neurilemmoma was initially mistaken for a dermoid cyst is described, highlighting diagnostic challenges in the submandibular region.

## Contribution

This paper presents a unique clinical case of neurilemmoma masquerading as a dermoid cyst, emphasizing diagnostic pitfalls in this anatomical region.

## Key findings

- The lesion was initially diagnosed as a dermoid cyst via ultrasonography but confirmed as neurilemmoma through histopathology.
- The mass was encapsulated and successfully excised without neurological deficits.
- The case underscores the importance of histopathological confirmation for accurate diagnosis in this region.

## Abstract

Neurilemmomas in the submental and submandibular region represent a diagnostic challenge, often mimicking more common superficial cysts. This is a case of neurilemmoma of the marginal mandibular branch of the facial nerve, initially diagnosed as a dermoid cyst via ultrasonography in a 65‐year‐old male with an 18‐month history of a painless 1.5‐cm mass. Histopathological examination of the excised lesion confirmed neurilemmoma. The mass was encapsulated and easily detached from the surrounding tissue; thus, successful excision without postoperative neurological deficits was ensured.

## Linked entities

- **Diseases:** neurilemmoma (MONDO:0002546), dermoid cyst (MONDO:0002378)

## Full-text entities

- **Genes:** S100A1 (S100 calcium binding protein A1) [NCBI Gene 6271] {aka S100, S100-alpha, S100A}
- **Diseases:** inflammation (MESH:D007249), trauma (MESH:D014947), epidermoid cyst (MESH:D004814), pain (MESH:D010146), cystic lesion (MESH:D052177), nerve damage (MESH:D000080902), infection (MESH:D007239), calcification (MESH:D002114), tumor (MESH:D009369), weakness (MESH:D018908), sensory deficit (MESH:D012678), weight loss (MESH:D015431), Neurilemmoma (MESH:D009442), Head and neck neurilemmomas (MESH:D006258), swelling (MESH:D004487), neurological complications (MESH:D002493), depression (MESH:D003866), Dermoid Cyst (MESH:D003884), neurological abnormality (MESH:D009461), fever (MESH:D005334), cysts (MESH:D003560), anterior chin lesion (MESH:D000094222)
- **Chemicals:** betel quid (-), ibuprofen (MESH:D007052), lignocaine (MESH:D008012), adrenaline (MESH:D004837), amoxicillin (MESH:D000658)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nicotiana tabacum (American tobacco, species) [taxon 4097]

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12961555/full.md

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Source: https://tomesphere.com/paper/PMC12961555