Growth Performance and Intestinal Health of Triploid Rainbow Trout (Oncorhynchus mykiss) Through Bile Acid Supplementation in Low Fishmeal Diets: Insights From Metabolomics, Microbiota, and Gene Expression
Huamin Wang, Siyuan Liu, Zhenhua Ma, Shidi Wang, Shuze Zhang, Shaoxia Lu, Shicheng Han, Haibo Jiang, Gefeng Xu, Hongbai Liu, Chang’an Wang
TL;DR
Adding 0.10% bile acid to low fishmeal diets improves growth and gut health in triploid rainbow trout.
Contribution
Demonstrates how bile acid supplementation enhances growth and intestinal health in trout on low fishmeal diets.
Findings
0.10% bile acid improved final body weight, growth rate, and condition factor in trout.
Bile acid reduced intestinal inflammation and improved lipid metabolism gene expression.
Microbial composition and metabolic pathways were significantly altered by bile acid supplementation.
Abstract
This research aimed to explore the impact of bile acid (BA) supplementation in low fishmeal diets on growth performance, serum biochemical indices, tissue morphology, lipid metabolism, gene expression, and gut microbiota in triploid rainbow trout (Oncorhynchus mykiss, initial weight 15.97 ± 1.4 g). The experimental design involved a low fishmeal diet (10%), and four treatment groups with BA additions (0.05%, 0.10%, 0.15%, and 0.20%) to the basal diet. The findings indicated that the group receiving 0.10% BA (G3) exhibited an enhancement in final body weight (FBW), specific growth rate (SGR), weight gain rate (WGR), and condition factor (CF), significantly outperforming the control group (G1, p < 0.05). 0.10% BA addition significantly increased whole‐body crude protein and lipid content. (p < 0.05). Serum analysis showed a significant reduction in total bilirubin (TBIL) and triglycerides…
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Taxonomy
TopicsAquaculture Nutrition and Growth · Aquaculture disease management and microbiota · Reproductive biology and impacts on aquatic species