# Bosutinib-induced palmoplantar keratoderma treated with acitretin

**Authors:** Ye Chua, Katharina Wiedemeyer, Julie Mervak, Sruthi Renati

PMC · DOI: 10.1016/j.jdcr.2026.01.033 · 2026-02-02

## Full-text entities

- **Genes:** BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}, ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) [NCBI Gene 25] {aka ABL, BCR-ABL, CHDSKM, JTK7, bcr/abl, c-ABL}
- **Diseases:** cutaneous AE (MESH:D018366), rash (MESH:D005076), eczematous eruptions (MESH:D017443), hyperkeratotic lesions (MESH:D009059), Philadelphia chromosome (MESH:D010677), cutaneous toxicities (MESH:D013262), erythema (MESH:D004890), Epidermal hyperplasia (MESH:D006965), scaling (MESH:C538175), lichenoid eruptions (MESH:D017512), PPK (MESH:D007645), hyperkeratotic skin (MESH:D012871), inflammatory (MESH:D007249), CML (MESH:D015464), hyperkeratosis (MESH:D017488), cutaneous AEs (MESH:D002318), drug eruption (MESH:D003875), cancer (MESH:D009369)
- **Chemicals:** lipid (MESH:D008055), imatinib (MESH:D000068877), olmutinib (MESH:C000617753), retinoid (MESH:D012176), tyrosine (MESH:D014443), steroids (MESH:D013256), Bosutinib (MESH:C471992), sorafenib (MESH:D000077157), Acitretin (MESH:D017255), hematoxylin and eosin (-), H&E (MESH:D006371), urea (MESH:D014508)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12961217/full.md

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Source: https://tomesphere.com/paper/PMC12961217