# Perioperative management of a patient with tuberculous destroyed lung and ascending aortic aneurysm undergoing a Bentall procedure: a case report

**Authors:** Huimin Liu, Qing Li, Sijia Wang, Weidong Fu, Zhujun Huang, Mingzhi Zheng, Liu Luo, Lin Tang

PMC · DOI: 10.3389/fcvm.2026.1762499 · Frontiers in Cardiovascular Medicine · 2026-02-19

## TL;DR

A rare case of a patient with lung damage from tuberculosis and an aortic aneurysm successfully underwent heart surgery with careful planning.

## Contribution

This case report presents a successful surgical management strategy for a rare combination of tuberculosis-related lung damage and aortic aneurysm.

## Key findings

- The patient underwent a Bentall procedure without tuberculosis reactivation or major complications.
- Multidisciplinary collaboration and customized perioperative strategies are crucial for managing such complex multimorbidities.
- Early diagnosis and timely surgery improve outcomes in patients with tuberculous destroyed lung and aortic aneurysm.

## Abstract

The coexistence of tuberculous destroyed lung (TDL) and ascending aortic aneurysm represents a rare multimorbidity, posing significant challenges for perioperative management in patients requiring cardiopulmonary bypass (CPB)-assisted major vascular surgery. The clinical manifestations of this polycoexisting disease may be asymptomatic or present as symptoms of one of the diseases or both. Currently, there is no universally accepted diagnostic protocol available for the definitive diagnosis of complex conditions such as tuberculosis and its comorbidities.

A 58-year-old woman presented with a 1-month history of cough, expectoration, chest tightness, and dyspnea, which had exacerbated over the preceding week. Pulmonary computed tomography revealed left lung fibrosis with architectural destruction, along with aneurysmal dilation of the ascending aorta. Her medical history included tuberculosis (diagnosed 20 years earlier and treated with anti-tuberculosis therapy for 6 months), hypertension (managed with levamlodipine besylate 5 mg daily), and recurrent pulmonary infections. After multidisciplinary evaluation, she underwent an elective Bentall procedure under CPB. Postoperatively, there was no evidence of tuberculosis reactivation or major complications, and she was discharged after 23 days of hospitalization.

Successful surgical intervention for TDL combined with thoracic aortic aneurysm is rarely reported. Early diagnosis and timely surgery are critical for improving patient outcomes. This case highlights the importance of multidisciplinary collaboration and customized perioperative strategies in managing such complex multimorbidities.

## Linked entities

- **Chemicals:** levamlodipine besylate (PubChem CID 11365087)
- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** thoracoabdominal aortic dissection (MESH:D000094631), pulmonary hypertension (MESH:D006976), chronic diseases (MESH:D002908), systole (MESH:D000092244), necrotic (MESH:D009336), aortic root aneurysm (MESH:D000094628), cardiac enlargement (MESH:D006331), Mycobacterium tuberculosis infection (MESH:D014376), tenderness (MESH:D063806), aortic insufficiency (MESH:D001022), enlargement of the left ventricle (MESH:D020257), tricuspid valves (MESH:D014262), sinus tachycardia (MESH:D013616), congestive heart failure (MESH:D006333), acidosis (MESH:D000138), dizziness (MESH:D004244), congenital heart defects (MESH:D006330), diastolic murmur (MESH:D006337), ulcer (MESH:D014456), cough (MESH:D003371), ascending aortic aneurysm (MESH:D000094625), chills (MESH:D023341), postoperative pulmonary complications (MESH:D011183), shortness of (MESH:C537327), Aneurysmal dilation (MESH:D002311), infection (MESH:D007239), cardiovascular complications (MESH:D002318), effusion (MESH:D000080324), pulmonary tuberculosis (MESH:D014397), pulmonary arterial hypertension (MESH:D000081029), mycoplasma infection (MESH:D009175), death (MESH:D003643), left ventricular hypertrophy (MESH:D017379), hypertension (MESH:D006973), deformity of the thorax (MESH:D019568), descending aortic aneurysms (MESH:D000094627), atelectasis (MESH:D001261), AAA (MESH:D017544), diseased aortic valve (MESH:D000082862), hypoxia (MESH:D000860), vomiting (MESH:D014839), regurgitation of (MESH:D008944), Pericardial effusion (MESH:D010490), ARDS (MESH:D012128), fever (MESH:D005334), bronchial stenosis/ (MESH:D003251), venous distension (MESH:D014647), aneurysm rupture (MESH:D017542), hemoptysis (MESH:D006469), hypercapnia (MESH:D006935), reactive hyperemia (MESH:D006940), mitral (MESH:D008946), chest tightness (MESH:D002637), cardiomyopathy (MESH:D009202), aortic stenosis (MESH:D001024), hypoxic damage (MESH:D002534), nausea (MESH:D009325), pleural effusion (MESH:D010996), left ventricular and right atrial enlargement (MESH:D018487), respiratory failure (MESH:D012131)
- **Chemicals:** Ice (MESH:D007053), heparin (MESH:D006493), tryptophan (MESH:D014364), Bentall (-), Amoxicillin (MESH:D000658), levamlodipine besylate (MESH:C000711385), Levofloxacin (MESH:D064704), histidine (MESH:D006639), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606], Mycoplasmoides pneumoniae (Filterable agent of primary atypical pneumonia, species) [taxon 2104]

## Full text

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## Figures

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12960574/full.md

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Source: https://tomesphere.com/paper/PMC12960574