# Weight-bearing computed tomography in knee pathologies: current evidence and future perspectives

**Authors:** Andre Giardino Moreira da Silva, Renata Vidal Leão, Carlos Felipe Teixeira Lobo, Enzo Tunala Mendonça, Camilo Partezani Helito

PMC · DOI: 10.3389/fsurg.2026.1769099 · Frontiers in Surgery · 2026-02-19

## TL;DR

This paper reviews how weight-bearing CT scans can improve knee diagnosis by capturing dynamic joint changes missed by traditional imaging methods.

## Contribution

The paper provides a comprehensive review of WBCT's clinical applications and identifies areas for future development in knee pathologies.

## Key findings

- WBCT captures dynamic joint changes missed by conventional imaging.
- WBCT is useful for evaluating knee osteoarthritis and postoperative outcomes.
- Standardized protocols and advanced image analysis are needed for broader adoption.

## Abstract

Weight-bearing computed tomography (WBCT) provides three-dimensional (3D), high-resolution imaging with patients in either a unipodal or bipodal stance, allowing visualization of dynamic joint alterations that might be missed in conventional radiographs or in non–weight-bearing exams, such as conventional computed tomography (CT) or magnetic resonance imaging (MRI) scans. Multiple lines of research are exploring its application for the evaluation of knee osteoarthritis, knee ligamentous instability, malalignment syndromes, patellofemoral disorders, and postoperative assessment following total knee arthroplasty. Despite its growing clinical utility, the development of standardized imaging protocols, broader accessibility, and integration with advanced image-analysis tools remain important areas for further progress. This review summarizes the current evidence supporting the clinical applications of WBCT in knee assessment and discusses future directions aimed at optimizing its role in personalized musculoskeletal care.

## Full-text entities

- **Diseases:** rotational abnormalities (MESH:D009759), Patellofemoral pathologies (MESH:D046788), coronal malalignment (MESH:D017760), chondral lesions (MESH:D009059), foot and ankle pathologies (MESH:D016512), cartilage damage (MESH:D002357), OA (MESH:D010003), pain (MESH:D010146), patellar dislocation (MESH:D031222), JSW (MESH:D008158), degenerative disease (MESH:D019636), ACL (MESH:D000070598), ACL insufficiency (MESH:D000309), ligament degeneration (MESH:D009410), Flexion deformity (MESH:D009140), tibial malrotation (MESH:C562456), internal (MESH:D000082122), subluxation (MESH:D004204), weakness of the hip abductors and external rotators (MESH:C536354), mechanical (MESH:D041781), impaired neuromuscular control (MESH:D009468), instability (MESH:D043171), aseptic loosening (MESH:D011475), osteophytes (MESH:D054850), CL (MESH:D002971), knee (MESH:D007718), meniscal (MESH:D010007), subchondral bone lesions (MESH:D001847), Knee osteoarthritis (MESH:D020370), medial compartment osteoarthritis (MESH:D003161), subchondral cysts (MESH:D001845)
- **Chemicals:** WBCT (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12960526/full.md

## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12960526/full.md

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Source: https://tomesphere.com/paper/PMC12960526