# Editorial: Sex as a biological variable in the neurocircuitry of motivated behavior

**Authors:** Paul Leon Brown, Polymnia Georgiou, Amy Stave Kohtz, Antoniette M. Maldonado-Devincci

PMC · DOI: 10.3389/fnbeh.2026.1802383 · Frontiers in Behavioral Neuroscience · 2026-02-19

## Full-text entities

- **Genes:** Ugt1a1 (UDP glucuronosyltransferase family 1 member A1) [NCBI Gene 24861] {aka UDPGT 1-1, Udpgt, Ugt1}, Cyp19a1 (cytochrome P450, family 19, subfamily a, polypeptide 1) [NCBI Gene 25147] {aka Aromatase, Cyp19, Cyp19a, p450arom}
- **Diseases:** impaired motivation (MESH:D060825), psychiatric (MESH:D001523), substance abuse (MESH:D019966), schizophrenia (MESH:D012559), craving (MESH:C564883), Parkinson's disease (MESH:D010300), Alcohol use disorder (MESH:D000437), depressive disorder (MESH:D003866), neurological diseases (MESH:D020271), cognitive symptoms (MESH:D019954)
- **Chemicals:** Cocaine (MESH:D003042), substance (MESH:C012600), AIE (-), oxycodone (MESH:D010098), dopamine (MESH:D004298), morphine (MESH:D009020), glutamate (MESH:D018698), ethanol (MESH:D000431), fadrozole (MESH:D017316)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12960293/full.md

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Source: https://tomesphere.com/paper/PMC12960293