# MTAS-MENA: adapting the Stroke Access Barrier Index (SABI) to enhance mechanical thrombectomy access in the Middle East and North Africa region

**Authors:** Ossama Yassin Mansour, Kaiz S. Asif, Violiza Inoa, Farid Aladham, Ibrahim Alnaami, Hosam Maher Al-Jehani, Abdulrahman Alshamy, Faisal Alghamdi, Ozlem Aykac, Mohamed Hamdy, Hany Hamadani, Mehdi Farhodi, Mahmoud Galal, Mohamed Ghorbani, Erdem Gurkas, Mohamed Alaa Habib, Nadia Hammami, Tamer Hassan, Farouk Hassan, Syed I. Hussain, Yahia Imam, Seby John, Wael Khalifa, Amina El Khamlichi, Amr Mahmoud, Ahmed Ossama, Mostafa Mahmoud, Ehab S. Mohamed, Nada Nasr, Atilla Ozcan Ozdemir, Umair Rashid, Salma Said, Abdulmonem Saied, Maher Saqqur, Khalid Sobh, Ryna Then, Gillian L. Gordon Perue, Mohammed Wasay, Hany Zaki Eldeen, Fawaz Al-Mufti, Santiago Ortega-Gutierrez, Sheila Martins, Dileep R. Yavagal, Ashfaq Shuaib

PMC · DOI: 10.3389/fneur.2026.1727476 · Frontiers in Neurology · 2026-02-19

## TL;DR

A new index was developed to assess barriers to stroke treatment access in the Middle East and North Africa region.

## Contribution

Adaptation and preliminary validation of the Stroke Access Barrier Index (SABI) for the MENA region.

## Key findings

- MENA region's median SABI score was 18.5, significantly lower than the global median of 22.0.
- Low EMS utilization and health literacy were consistent issues across all income levels.
- Urban facilities scored higher than rural ones in SABI assessments.

## Abstract

We developed and preliminarily validated the Stroke Access Barrier Index (SABI), adapted from the global MTAS framework, then applied it to assess potential barriers to mechanical thrombectomy access in the MENA region.

Cross-sectional survey with embedded instrument development and validation study. We surveyed 352 stroke and neurointerventional facility directors across the Middle East and North Africa (MENA) region, defined as 22 countries/territories, with responses obtained from 17 countries (March–June 2024), receiving 102 responses (29%). The SABI tool evaluates 12 attributes scored 0-3, yielding a total score from 0-36. Emergency medical services (EMS) utilization and health literacy were key measures.

The median SABI score for the MENA region was 18.5 (IQR: 10.0–24.0; 95% CI: 16.8–20.2), significantly lower (p < 0.001) than the global median of 22.0 (IQR: 14.0-28.0; 95% CI: 21.3–22.7). High-income countries scored 24.0, while low-income countries scored 10.0. Physical barriers (median: 4.5/9.0) and sociocultural barriers (median: 4.0/9.0) were most prominent. EMS utilization (median: 1.0) and health literacy (median: 1.0) were consistently low across all income levels. Urban facilities (median: 20.5) substantially outperformed rural facilities (median: 13.0, p < 0.001).

The SABI provides an exploratory framework for identifying potential MT access barriers in the MENA region. While preliminary findings suggest substantial challenges (median score 18.5), these results require validation through prospective studies linking scores to actual MT utilization and patient outcomes. This initial assessment may guide hypothesis generation for future intervention studies.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** LVO (MESH:C536223), Stroke (MESH:D020521), MENA (MESH:D018352), disabilities (MESH:D009069), MT (MESH:D041781)
- **Chemicals:** MT (-)
- **Species:** Meleagris gallopavo (common turkey, species) [taxon 9103], Homo sapiens (human, species) [taxon 9606], Ostreobium sp. M (species) [taxon 2268118], Fascellina sp. A (species) [taxon 1373661]

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## Figures

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12960120/full.md

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Source: https://tomesphere.com/paper/PMC12960120