# Case Report: long-term calcaemia management in a dog after thyroidectomy and parathyroidectomy

**Authors:** Alessio Ruggiero, Camilla Sangiuliano, Monica Isabella Cutrignelli, Luigi Navas, Domenico Bergero

PMC · DOI: 10.3389/fvets.2026.1663570 · Frontiers in Veterinary Science · 2026-02-19

## TL;DR

A dog with low blood calcium after thyroid and parathyroid surgery was successfully managed with a customized diet and supplements over six months.

## Contribution

A tailored nutritional strategy for long-term hypocalcaemia management in a canine patient after thyroidectomy and parathyroidectomy.

## Key findings

- The dog maintained stable calcium levels with a homemade diet and calcium supplements.
- Vitamin D3 and phosphorus levels were also stabilized over six months.
- The tailored diet helped manage hyporexia and long-term calcaemia.

## Abstract

This report describes a canine case of severe hypocalcaemia following the surgical removal of a thyroid lobe and the ipsilateral parathyroid glands for thyroid carcinoma. After initial stabilisation with intravenous calcium gluconate, the dog was initially managed with a commercial diet, and subsequently with a homemade diet, which provided 3.72 and 3.30 g/1,000 kcal ME of calcium, 376 and 295 IU of vitamin D3, and 2.48 and 1.50 g/1,000 kcal metabolisable energy (ME) of phosphorus, respectively. Both nutritional plans were supplemented with calcium carbonate (200 mg/day) and calcitriol (9.84 IU/day) to maintain normocalcaemia. A tailored, homemade diet was formulated to address the onset of hyporexia. The patient maintained stable serum calcium, phosphorus, and total 25(OH) vitamin D concentrations over a mid-term follow-up period of 6 months.

## Linked entities

- **Chemicals:** calcium gluconate (PubChem CID 9290), calcium carbonate (PubChem CID 10112), calcitriol (PubChem CID 5280453), vitamin D3 (PubChem CID 5280795)
- **Diseases:** thyroid carcinoma (MONDO:0015075)
- **Species:** Canis lupus familiaris (taxon 9615)

## Full-text entities

- **Genes:** PTH (parathyroid hormone) [NCBI Gene 403986], ALB (albumin) [NCBI Gene 403550] {aka CSA}, CALCA (calcitonin related polypeptide alpha) [NCBI Gene 403946] {aka CALC, CCALCI, CGRP-I, CGRP1}, STAT1 (signal transducer and activator of transcription 1) [NCBI Gene 488449], ALPL (alkaline phosphatase, biomineralization associated) [NCBI Gene 403548] {aka ALP}, FGF23 (fibroblast growth factor 23) [NCBI Gene 611773]
- **Diseases:** uremic crises (MESH:D013224), biliary suffering (MESH:D010146), urinary obstruction (MESH:D001748), hypercalcaemic condition (MESH:D020763), anorexia (MESH:D000855), CKD (MESH:D051436), polyuria (MESH:D011141), gallstones (MESH:D042882), calcification (MESH:D002114), Thyroid neoplasia (MESH:D009369), skeletal disorders (MESH:C564967), renal failure (MESH:D051437), D (MESH:D014808), lithiasis (MESH:D020347), cardiac arrhythmia (MESH:D001145), nausea (MESH:D009325), systemic diseases (MESH:D034721), gallbladder mucocele (MESH:D009078), muscle mass reduction (MESH:C536030), paraneoplastic hypercalcaemia (MESH:D010257), proteinuria (MESH:D011507), hypoparathyroidism (MESH:D007011), follicular thyroid carcinoma (MESH:D018263), Renal calcifications (MESH:C565478), tremors (MESH:D014202), nutritional deficiencies (MESH:D044342), bladder stones (MESH:D001744), ataxia (MESH:D001259), thyroid carcinoma (MESH:D013964), metastasis (MESH:D009362), muscle spasms (MESH:D013035), urolithiasis (MESH:D052878), weight loss (MESH:D015431), polydipsia (MESH:D059606), endocrine dysfunctions (MESH:D004700), gastrointestinal disorders (MESH:D005767), cholestasis (MESH:D002779), renal and hepatic failure (MESH:D017093), muscle loss (MESH:D009135), mucosal abnormalities (MESH:D052016), Disorders of calcium homeostasis (MESH:D002128), kidney damage (MESH:D007674), IRIS (MESH:C000719191), tissue (MESH:D017695), cholelithiasis (MESH:D002769)
- **Chemicals:** zinc (MESH:D015032), Phosphorus (MESH:D010758), maltodextrin (MESH:C008315), phosphate (MESH:D010710), sugars (MESH:D000073893), Vitamin D (MESH:D014807), chondroitin sulphate (MESH:D002809), Calcium carbonate (MESH:D002119), triglyceride (MESH:D014280), potassium phosphate (MESH:C013216), SDMA (MESH:C024917), cortisol (MESH:D006854), calcium gluconate (MESH:D002125), stearic acid (MESH:C031183), iron (MESH:D007501), calcium oxalate (MESH:D002129), salmon oil (MESH:C030341), cholesterol (MESH:D002784), copper (MESH:D003300), calcium phosphate (MESH:C020243), sodium (MESH:D012964), L-carnitine (MESH:D002331), 25(OH) vitamin D (-), carbohydrates (MESH:D002241), xylo-oligosaccharides (MESH:C570991), corn starch (MESH:D013213), ergocalciferol (MESH:D004872), cholecalciferol (MESH:D002762), urea (MESH:D014508), corn oil (MESH:D003314), lipids (MESH:D008055), beta-carotene (MESH:D019207), taurine (MESH:D013654), Ca (MESH:D002118), magnesium (MESH:D008274), glucosamine (MESH:D005944), creatinine (MESH:D003404), 1,25-dihydroxycholecalciferol (MESH:D002117)
- **Species:** Malus domestica (apple, species) [taxon 3750], Beta vulgaris (beet, species) [taxon 161934], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Canis lupus familiaris (dog, subspecies) [taxon 9615], Citrus (genus) [taxon 2706], Allium sativum (garlic, species) [taxon 4682], Meleagris gallopavo (common turkey, species) [taxon 9103], Daucus carota (carrot, species) [taxon 4039], Powellomyces sp. EA (species) [taxon 252690], Solanum lycopersicum (tomato, species) [taxon 4081], Homo sapiens (human, species) [taxon 9606], Yucca schidigera (Mohave yucca, species) [taxon 334597], Oryza sativa (Asian cultivated rice, species) [taxon 4530], PX clade (clade) [taxon 569578], Solanum tuberosum (potatoes, species) [taxon 4113], Gallus gallus (bantam, species) [taxon 9031], Ananas comosus (pineapple, species) [taxon 4615]

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12960099/full.md

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Source: https://tomesphere.com/paper/PMC12960099