This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells
Abstract
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Taxonomy
TopicsFOXO transcription factor regulation · Medicinal Plants and Bioactive Compounds · Antioxidants, Aging, Portulaca oleracea
After this article [1,2] was published, concerns were raised regarding results presented in Figs 2–3 and 5–7. Specifically,
The authors did not respond to editorial request for comment on these concerns.
In light of the above concerns which call into question the integrity and reliability of [1,2], the PLOS One Editors retract this article.
All authors either did not respond directly or could not be reached.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Zhang S, Zhao Y, Xu M, Yu L, Zhao Y, Chen J, et al. RETRACTD: Fox O 3a modulates hypoxia stress induced oxidative stress and apoptosis in cardiac microvascular endothelial cells. P Lo S One. 2013;8(11):e 80342. doi: 10.1371/journal.pone.0080342 24278276 PMC 3835407 · doi ↗ · pubmed ↗
- 2Zhang S, Zhao Y, Xu M, Yu L, Zhao Y, Chen J, et al. Correction: Fox O 3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells. P Lo S One. 2013;8(12). doi: 10.1371/annotation/1c 419628-f 1b 5-45de-9f 8a-43f 834309 ebb 29161729 PMC 5703077 · doi ↗ · pubmed ↗
- 3Chen C, Yao L, Cui J, Liu B. Retracted Paper - Fisetin Protects against Intracerebral Hemorrhage-Induced Neuroinflammation in Aged Mice. Cerebrovasc Dis. 2018;45(3–4):154–61. doi: 10.1159/000488117 29587289 · doi ↗ · pubmed ↗
- 4Chen C, Yao L, Cui J, Liu B. Retraction Statement: Paper by Cheng Chen, Li Yao, Jing Cui, and Bao Liu entitled “Fisetin Protects against Intracerebral Hemorrhage-Induced Neuroinflammation in Aged Mice”. Cerebrovascular Diseases. 2024;53(6): 794. doi: 10.1159/000540449 29587289 · doi ↗ · pubmed ↗
- 5Shen L-D, Qi W-H, Bai J-J, Zuo C-Y, Bai D-L, Gao W-D, et al. Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX 4 inactivation. Anat Rec (Hoboken). 2021;304(2):313–22. doi: 10.1002/ar.24378 31961485 · doi ↗ · pubmed ↗
- 6Shen L-D, Qi W-H, Bai J-J, Zuo C-Y, Bai D-L, Gao W-D et al. RETRACTED: Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX 4 inactivation. Rec (Hoboken). 2021;304(12):2892. doi: 10.1002/ar.24804 31961485 · doi ↗ · pubmed ↗
- 7Peng C, Ma J, Gao X, Tian P, Li W, Zhang L. High glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by Fox O 3a. P Lo S One. 2013;8(11):e 79739. doi: 10.1371/journal.pone.0079739 24260294 PMC 3832590 · doi ↗ · pubmed ↗
- 8Liu W, Miao Y, Zhang L, Xu X, Luan Q. Mi R-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis. Bioengineered. 2020;11(1):189–200. doi: 10.1080/21655979.2020.1729322 32050841 PMC 7039642 · doi ↗ · pubmed ↗