# Inflammatory Biomarkers Decay After First‐Line Antiretroviral Therapy Initiation With Dolutegravir/Lamivudine or Bictegravir/Emtricitabine/Tenofovir Alafenamide in Persons With HIV: A Substudy of a Randomized Clinical Trial

**Authors:** Analuz Fernandez, Sofía Scevola, Raul Rigo Bonin, Maria Saumoy, Arkaitz Imaz, Daniel Podzamczer, Juan Tiraboschi

PMC · DOI: 10.1002/hsr2.71584 · Health Science Reports · 2026-03-04

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, TIGIT (T cell immunoreceptor with Ig and ITIM domains) [NCBI Gene 201633] {aka VSIG9, VSTM3, WUCAM}, VCAM1 (vascular cell adhesion molecule 1) [NCBI Gene 7412] {aka CD106, INCAM-100}, CAT (catalase) [NCBI Gene 847], CD14 (CD14 molecule) [NCBI Gene 929], CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}, IL10 (interleukin 10) [NCBI Gene 3586] {aka CSIF, GVHDS, IL-10, IL10A, TGIF}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, PDCD1 (programmed cell death 1) [NCBI Gene 5133] {aka ADMIO4, AIMTBS, CD279, PD-1, PD1, SLEB2}, CD38 (CD38 molecule) [NCBI Gene 952] {aka ADPRC 1, ADPRC1, cADPR1}, CD163 (CD163 molecule) [NCBI Gene 9332] {aka M130, MM130, SCARI1}, CXCL8 (C-X-C motif chemokine ligand 8) [NCBI Gene 3576] {aka GCP-1, GCP1, IL8, LECT, LUCT, LYNAP}, FABP2 (fatty acid binding protein 2) [NCBI Gene 2169] {aka FABPI, I-FABP}
- **Diseases:** cardiovascular disease (MESH:D002318), coagulation (MESH:D001778), infections (MESH:D007239), COVID-19 infection (MESH:D000086382), HIV (MESH:D015658), sepsis (MESH:D018805), Inflammatory (MESH:D007249), neurocognitive decline (MESH:D060825), cancer (MESH:D009369), opportunistic infections (MESH:D009894), AIDS (MESH:D000163), HIV persistence (MESH:D016263)
- **Chemicals:** ABC (MESH:C106538), BIC/FTC (-), Emtricitabine (MESH:D000068679), BIC (MESH:C100119), Tenofovir Alafenamide (MESH:C442442), EDTA (MESH:D004492), Bictegravir (MESH:C000620396), DTG (MESH:C562325), 3TC (MESH:D019259)
- **Species:** Homo sapiens (human, species) [taxon 9606], Hepatitis B virus (no rank) [taxon 10407], Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12959470/full.md

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Source: https://tomesphere.com/paper/PMC12959470