# Isolated Anterior Mesenteric Neurofibroma: A Rare Manifestation of Neurofibromatosis Type 1

## TL;DR

A rare case of a mesenteric neurofibroma in a child with Neurofibromatosis Type 1 is reported, diagnosed through imaging and confirmed by pathology.

## Contribution

This case highlights an uncommon manifestation of NF1 in the gastrointestinal tract, specifically an isolated jejunal mesenteric neurofibroma.

## Key findings

- An isolated jejunal mesenteric neurofibroma was diagnosed in a nine-year-old child with NF1.
- Chronic abdominal pain led to imaging and histopathological confirmation of the tumor.
- The case underscores the variability and rarity of gastrointestinal manifestations in NF1.

## Abstract

Neurofibromatosis type 1 (NF1), also known as Von Recklinghausen disease, is a multisystemic, hereditary, autosomal dominant condition. It is caused by the development of tumors in the nervous system, resulting from mutations in the NF1 gene located on chromosome 17q11.2. Gastrointestinal involvement is mainly extraperitoneal, with mesentery lesions being the least common. We report a case of an isolated jejunal mesenteric neurofibroma diagnosed by ultrasound and CT scan and confirmed by histopathological examination in a nine-year-old child with diffuse café-au-lait spots who presented with chronic abdominal pain.