# Editorial: Salt-sensitive hypertension: mechanisms, therapeutics, and beyond

**Authors:** Mohammad Saleem, Sepiso K. Masenga, Riyaz Mohamed, Jing O. Wu

PMC · DOI: 10.3389/fphar.2026.1790409 · Frontiers in Pharmacology · 2026-02-18

## Full-text entities

- **Genes:** SSBP1 (single stranded DNA binding protein 1) [NCBI Gene 6742] {aka Mt-SSB, OPA13, SOSS-B1, SSBP, mtSSB}, TRPV1 (transient receptor potential cation channel subfamily V member 1) [NCBI Gene 7442] {aka VR1}, SCNN1B (sodium channel epithelial 1 subunit beta) [NCBI Gene 6338] {aka BESC1, ENaCb, ENaCbeta, LIDLS1, PHA1B2, SCNEB}
- **Diseases:** diastolic dysfunction (MESH:D018487), and renal (MESH:D006030), inflammation (MESH:D007249), reduced salt taste perception (MESH:D013651), myocardial fibrosis (MESH:D005355), endothelial dysfunction (MESH:D014652), heart failure (MESH:D006333), cardiac remodeling (MESH:D020257), HIV (MESH:D015658), Hypertension (MESH:D006973), cardiovascular disease (MESH:D002318), end-organ damage (MESH:C564816), and vascular dysfunction (MESH:D002561)
- **Chemicals:** Salt (MESH:D012492), aldosterone (MESH:D000450), 23Na (-), potassium (MESH:D011188), sodium (MESH:D012964)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12959267/full.md

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Source: https://tomesphere.com/paper/PMC12959267