# Pyometra Presenting as a Right-Lower-Quadrant Abdominal Mass With Right-Sided Bowel Dilatation on Abdominal Radiography: A Case Report

**Authors:** Seena Sugathan, Matthew D Parkinson, Syed O Husain, Bushra Jamil

PMC · DOI: 10.7759/cureus.102831 · Cureus · 2026-02-02

## TL;DR

An 81-year-old woman with sepsis and bowel issues was found to have pyometra, a rare uterine infection, highlighting the need for early pelvic imaging in similar cases.

## Contribution

This case report emphasizes pyometra as a critical differential diagnosis in elderly women with persistent sepsis and bowel symptoms.

## Key findings

- Pyometra can mimic gastrointestinal issues and delay diagnosis in elderly patients.
- Abdominal X-ray showed right-sided bowel dilatation, while MRI confirmed pyometra with air-fluid levels.
- Conservative management was chosen due to the patient's frailty, showing transient improvement.

## Abstract

Pyometra is an uncommon uterine infection that predominantly affects postmenopausal females. It can present with non-specific features and may at times mimic gastrointestinal pathology, delaying diagnosis. An 81-year-old female with multiple comorbidities and frailty presented to the emergency department with two weeks of poor oral intake and reduced mobility. She was treated as having sepsis of unclear source with suspected respiratory infection. Despite broad-spectrum intravenous antibiotics, she deteriorated clinically with persistently raised inflammatory markers. She developed abdominal discomfort, constipation, and then abdominal distension and right-sided abdominal tenderness. An abdominal X-ray showed dilated bowel loops on the right. Pelvic magnetic resonance imaging (MRI) demonstrated a markedly distended uterine cavity containing a large fluid collection with an air-fluid level and restricted diffusion, consistent with pyometra. Malignancy could not be excluded on imaging. The case was discussed with gynaecology and microbiology, and antibiotics were escalated. A best interests meeting concluded that definitive management with uterine drainage was too invasive given her frailty and unlikely tolerance. She was managed conservatively with intravenous antibiotics, with transient improvement in delirium and inflammatory markers. This case highlights pyometra as an important differential diagnosis in elderly women presenting with abdominal symptoms and bowel dilatation on imaging. Early pelvic imaging should be considered when sepsis persists without a clear source.

## Linked entities

- **Diseases:** pyometra (MONDO:0000497)

## Full-text entities

- **Diseases:** tubo-ovarian abscesses (MESH:D010049), fever (MESH:D005334), fungal infection (MESH:D009181), septic shock (MESH:D012772), seizure (MESH:D012640), cervical stenosis (MESH:D002575), frailty (MESH:D000073496), sepsis (MESH:D018805), Mass (MESH:C536030), uterine perforation (MESH:D014595), ejection murmur (MESH:D054160), Abdominal Mass (MESH:D000007), AS (MESH:D001024), bleeding (MESH:D006470), degenerated fibroids (MESH:D007889), groin rash (MESH:D005076), DMT2 (MESH:D003924), colonic polyp (MESH:D003111), constipation (MESH:D003248), ovarian tumours (MESH:D010051), confusion (MESH:D003221), tenderness (MESH:D063806), stroke (MESH:D020521), delirium (MESH:D003693), bowel perforation (MESH:D057112), malignancy (MESH:D009369), peritonitis (MESH:D010538), gastrointestinal (MESH:D005767), uterine infection (MESH:D007239), bowel dilatation (MESH:D002311), gynecologic malignancy (MESH:D005833), atrophic (MESH:D020966), Idiopathic pyometra (MESH:D055112), Abdominal pain (MESH:D015746), dehydrated (MESH:D003681), Inflammatory (MESH:D007249), appendicitis (MESH:D001064), respiratory infection (MESH:D012141), endometrial and cervical cancer (MESH:D002583), vascular dementia (MESH:D015140)
- **Chemicals:** amoxicillin/clavulanic acid (MESH:D019980), piperacillin/tazobactam (MESH:D000077725), metronidazole (MESH:D008795), cefuroxime (MESH:D002444)
- **Species:** Bacteroides fragilis (species) [taxon 817], Homo sapiens (human, species) [taxon 9606], Escherichia coli (E. coli, species) [taxon 562]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12959231/full.md

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Source: https://tomesphere.com/paper/PMC12959231