# Methodological concerns regarding supraphysiological histidine concentrations in HCC immunometabolism studies: an evidence-based discussion

**Authors:** Chenyang Ma, Xiaofei Zhu

PMC · DOI: 10.1186/s12967-026-07928-2 · Journal of Translational Medicine · 2026-03-04

## Full-text entities

- **Diseases:** HCC (MESH:D006528), cytotoxic (MESH:D064420)
- **Chemicals:** Histidine (MESH:D006639), amino acid (MESH:D000596)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12958498