# Scarlet Fever in Iran During the Qajar Period (1796 to 1925 AD); A Brief Historical Review

**Authors:** Seyyed Alireza Golshani, Ghobad Mansourbakht, Mehrdad Haghighi

PMC · DOI: 10.34172/aim.35069 · Archives of Iranian Medicine · 2025-11-01

## TL;DR

This paper reviews the history of scarlet fever in Iran during the Qajar period, comparing traditional and European medical approaches.

## Contribution

The study provides a comparative historical analysis of scarlet fever treatment and understanding in Iran using Persian and European sources.

## Key findings

- Scarlet fever outbreaks in Iran during the Qajar era were severe and often fatal before antibiotics.
- Both traditional and European medicine recognized similar symptoms but used different treatment approaches.
- Outbreaks peaked in cold months and primarily affected children aged 5–15 years.

## Abstract

Scarlet fever, known in Persian as "Tab-e Sorkh," is a bacterial infection caused by Streptococcus pyogenes. During the Qajar era (1796–1925), it was often deadly and reached pandemic levels in the 19th century. Both traditional Iranian and European medicine described its symptoms, but few comparative studies exist. By analyzing historical Persian texts, European medical reports, and modern literature, this study compares how the disease was understood and treated. Symptoms like rash and fever were widely recognized, and mortality was high before antibiotics. Traditional treatments followed humoral theory, including herbal remedies and bloodletting. Outbreaks peaked in cold months, mostly affecting children aged 5–15 years — a pattern seen in both medical systems. From the 1820s to 1880s, scarlet fever caused global outbreaks, especially in Iran. This research shows how combining historical perspectives can deepen our understanding of infectious diseases and their treatment across time.

## Linked entities

- **Diseases:** scarlet fever (MONDO:0005952)

## Full-text entities

- **Diseases:** leprosy (MESH:D007918), typhus (MESH:D014438), glomerulonephritis (MESH:D005921), pharyngitis (MESH:D010612), malnutrition (MESH:D044342), Benign scarlet fever (MESH:D012541), exanthematous (MESH:D056150), Eruptive Diseases (MESH:D003875), infected (MESH:D007239), endocardial damage (MESH:D004695), Amebic dysentery (MESH:D004404), renal involvement (MESH:C565423), plague (MESH:D010930), measles (MESH:D008457), bacterial infection (MESH:D001424), hypersensitivity (MESH:D004342), typhoid (MESH:D014435), smallpox (MESH:D012899), Pemphigus contagiosus (MESH:D010392), septicemia (MESH:D018805), infectious disease (MESH:D003141), exanthematous diseases (MESH:D004194), Skin Diseases (MESH:D012871), Russian flu (MESH:D007251), Malignant (MESH:D009369), rheumatic fever (MESH:D012213), chickenpox (MESH:D002644), alopecia (MESH:D000505), cholera (MESH:D002771), urticaria (MESH:D014581), streptococcal infections (MESH:D013290), lymphadenopathy (MESH:D008206), Rash (MESH:D005076), Desquamation of (MESH:D017490), pneumonia (MESH:D011014), delirium (MESH:D003693), Fever (MESH:D005334), otitis media (MESH:D010033)
- **Chemicals:** Buthorat (-), penicillin (MESH:D010406)
- **Species:** Homo sapiens (human, species) [taxon 9606], Streptococcus sp. 'group A' (species) [taxon 36470], Streptococcus pyogenes (species) [taxon 1314]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12958424/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12958424/full.md

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Source: https://tomesphere.com/paper/PMC12958424