# Traumatic Liver Injury With Delayed Bleeding After Extracorporeal Cardiopulmonary Resuscitation

**Authors:** Akihito Deguchi, Hirohisa Fujikawa, Kazuaki Ueki, Chihiro Hirata, Michihiro Tamai

PMC · DOI: 10.7759/cureus.102814 · Cureus · 2026-02-02

## TL;DR

A patient developed delayed liver bleeding after a life-saving heart procedure and required emergency treatment to stop the bleeding and survive.

## Contribution

This case highlights the risk of delayed traumatic liver injury after E-CPR and the effectiveness of early minimally invasive intervention.

## Key findings

- Traumatic liver injury can occur after E-CPR and may present with delayed bleeding.
- Nonoperative management may fail in some cases, requiring embolization for hemostasis.
- Early intervention improved hemodynamic stability and neurological outcomes.

## Abstract

Although chest compressions are a crucial component of cardiopulmonary resuscitation (CPR), they can sometimes result in traumatic complications. The incidence of hepatic injury, although rare relative to rib and sternal fractures, may result in severe hemorrhage and may be fatal, especially in patients receiving concomitant antiplatelet and anticoagulant therapy. This risk is particularly pronounced after extracorporeal CPR (E-CPR), as dual antiplatelet therapy (DAPT) for acute coronary syndrome and unfractionated heparin for preventing circuit thrombosis are required. We present a case of traumatic liver injury (TILI) following E-CPR for refractory ventricular fibrillation (VF) owing to acute myocardial infarction (AMI). In the absence of contrast extravasation on contrast-enhanced computed tomography (CT), nonoperative management was initially selected. However, the patient became transfusion-dependent despite receiving conservative management, prompting transcatheter arterial embolization (TAE), which resulted in rapid hemodynamic stabilization. The patient survived with a favorable neurological outcome. The present case highlights the need for maintaining a high index of suspicion for occult bleeding after E-CPR and underpins early minimally invasive hemostatic interventions, even in the absence of radiographic extravasation.

## Linked entities

- **Diseases:** acute coronary syndrome (MONDO:0005542), acute myocardial infarction (MONDO:0004781), ventricular fibrillation (MONDO:0000190)

## Full-text entities

- **Diseases:** coronary stent thrombosis (MESH:D003328), pulmonary thromboembolism (MESH:D011655), hypotension (MESH:D007022), neurological deficits (MESH:D009461), VF (MESH:D014693), blunt trauma (MESH:D014949), rib (MESH:C537613), intra-abdominal bleeding (MESH:D000082122), organ injuries (MESH:D009102), arrhythmias (MESH:D001145), sternal fractures (MESH:C537489), visceral organ damage (MESH:D000092124), Bleeding (MESH:D006470), Contrast (MESH:D005119), TAE (MESH:D004617), DCS (MESH:C536560), TLI (MESH:D017093), hepatic injury (MESH:D056486), chest pain (MESH:D002637), pseudoaneurysm (MESH:D017541), AMI (MESH:D009203), hemorrhagic shock (MESH:D012771), occlusion of the proximal right coronary artery (MESH:D054059), CPR (MESH:D006323), abdominal compartment syndrome (MESH:D059325), microvascular injury (MESH:D017566), Cerebral Performance (MESH:D002547), hemoperitoneum (MESH:D006465), hematoma (MESH:D006406), thrombosis (MESH:D013927), anemia (MESH:D000740), shock (MESH:D012769), ascites (MESH:D001201), Skeletal injuries (MESH:D014947), acute coronary syndrome (MESH:D054058), fractures (MESH:D050723)
- **Chemicals:** heparin (MESH:D006493), norepinephrine (MESH:D009638), aspirin (MESH:D001241), E (MESH:D004540), amiodarone (MESH:D000638), epinephrine (MESH:D004837), VA (-), prasugrel (MESH:D000068799), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12958088/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12958088/full.md

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Source: https://tomesphere.com/paper/PMC12958088