# Cervical Cancer Screening in Uganda: Determinants of Past Screening and Post-Education Uptake; A Cross-Sectional Survey

**Authors:** Ali Ssetaala, Ibrahim Muwonge, Dorcus Namulwa, Nasimu Kyakuwa, Mathias Wambuzi, Gertrude Nanyonjo, Brenda Okech, Elien De Paepe, Heleen Vermandere, Olivier Degomme

PMC · DOI: 10.1177/10732748261427062 · Cancer Control: Journal of the Moffitt Cancer Center · 2026-03-03

## TL;DR

This study explores factors influencing cervical cancer screening in Uganda and finds that socioeconomic status and awareness significantly impact screening uptake.

## Contribution

The study identifies specific socioeconomic and informational factors associated with cervical cancer screening uptake in Uganda.

## Key findings

- Only 5.3% of participants were aware that HPV causes cervical cancer.
- Cervical cancer screening uptake increased to 40.3% after information provision.
- Higher income and prior screening experience are strongly associated with increased screening uptake.

## Abstract

Cervical cancer (CC) is the leading cause of cancer-related deaths among women in Uganda, largely due to late diagnosis. CC screening (CCS) is key to preventing these deaths. Awareness of past CCS, its determinants, and uptake of CCS after receiving information is crucial to informing prevention programming.

A two-phase community based cross-sectional survey was conducted among 600 randomly selected women aged 25-65 years, from two Ugandan districts (Mukono and Wakiso). Participants completed a baseline questionnaire that assessed their knowledge, attitudes, and past practices related to CCS. Information on cervical cancer and screening was provided during and after the survey to encourage uptake, which was assessed three months later. Logistic regression identified factors associated with past CCS and follow-up uptake after information giving.

Few women [5.3%, (32/600)] were aware that Human Papillomavirus (HPV) infection causes CC. Past CCS was low [22.3%, (134/600)], associated with the age group 36-65 years (AOR= 1.9, 95% CI 1.2 - 3.2), owning a mobile telephone (AOR = 2.3, 95% CI 1.4 - 3.9), residing in a household headed by someone with tertiary or higher education (AOR=2.6, 95% CI 1.3 - 5.0), self-reported HIV infection (AOR=10.5, 95% CI 5.2 - 21.3), awareness of the location of CCS services (AOR=3.2, 95% CI 1.3 - 7.8), and awareness that accessing the CCS location was not expensive (AOR=2.3, 95% CI 1.3 - 4.0).

The uptake of CCS following information provision was 40.3%, (236/585), associated with employment (AOR=2.7, 95% CI 1.2 - 5.8), moderate-high income (AOR=1.6, 95% CI 1.0 - 2.6), and prior receipt of CCS services (AOR 6.7, 95% CI 4.0 -11.2).

CCS remains low but is higher among women with better socioeconomic status, awareness of services, and HIV infection. Targeted strategies addressing awareness and motivating women to get screened can boost screening uptake.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974), HIV infection (MONDO:0005109)

## Full-text entities

- **Genes:** CCS (copper chaperone for superoxide dismutase) [NCBI Gene 9973], DLAT (dihydrolipoamide S-acetyltransferase) [NCBI Gene 1737] {aka DLTA, E2, PBC, PDC-E2, PDCE2}, TRA (T cell receptor alpha locus) [NCBI Gene 6955] {aka IMD7, TCRA, TRA@}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** HIV (MESH:D015658), infection (MESH:D007239), precancerous (MESH:D011230), deaths (MESH:D003643), Pelvic pain (MESH:D017699), vaginal bleeding (MESH:D014592), cervical carcinogenesis (MESH:D063646), AIDS (MESH:D000163), lesions (MESH:D009059), bleeding (MESH:D006470), ORCID iDs (MESH:C535742), sexually transmitted diseases (MESH:D012749), CC (MESH:D009369), CC (MESH:D002583), PAP (OMIM:102200)
- **Chemicals:** PAP (MESH:D010724), Chemical (-), Acetic Acid (MESH:D019342)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus 1 (no rank) [taxon 11676], Human papillomavirus (species) [taxon 10566]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12957613/full.md

## References

53 references — full list in the complete paper: https://tomesphere.com/paper/PMC12957613/full.md

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Source: https://tomesphere.com/paper/PMC12957613