# Long-Term Outcomes of One-Anastomosis Gastric Bypass: A Systematic Review of Studies with at Least 10 Years of Follow-Up

**Authors:** Adam Abu-Abeid, Andrei Keidar, Shiran Gabay, Jonathan Benjamin Yuval, Nir Messer, Mati Shnell, Shai Meron Eldar, Avner Leshem

PMC · DOI: 10.1007/s11695-025-08479-z · Obesity Surgery · 2026-01-05

## TL;DR

This study reviews long-term outcomes of one-anastomosis gastric bypass surgery, showing it remains effective and safe over ten years.

## Contribution

The paper provides the first systematic review of OAGB outcomes with at least 10 years of follow-up.

## Key findings

- OAGB resulted in a mean total weight loss of 31.1% over ten years.
- Over 50% of patients experienced remission of obesity-related diseases like diabetes and hypertension.
- Approximately 5.2% of patients required conversion or revisional surgery.

## Abstract

One anastomosis gastric bypass (OAGB) is increasingly becoming popular worldwide and is considered a safe and effective procedure. However, data regarding long-term efficacy is lacking. We performed a systematic review of articles reporting outcomes in patients with a minimum follow-up of 10 years. Five retrospective studies comprising 1,750 patients met the inclusion criteria. Overall, the weighted mean percentage of total weight loss was 31.1% ( range 29.6–32.1), and remission rates of type 2 diabetes and hypertension ranged from 70.8 to 90% and 56.7–85%, respectively. Conversion or revisional surgery following OAGB was required in 5.2% ( range 3.3–6.4%) of patients on average. This systematic review suggests that OAGB remains a relatively effective and safe procedure after 10 years.

OAGB resulted in a mean total weight loss of 31.1% in a > 10-year follow-up.

OAGB caused the resolution of obesity related diseases in > 50% of patients.

The rate of conversion surgery was 3.3–6.4%.

OAGB is safe and effective after ten years.

## Linked entities

- **Diseases:** type 2 diabetes (MONDO:0005148)

## Full-text entities

- **Diseases:** type 2 diabetes (MESH:D003924), Anastomosis (MESH:C563598), weight loss (MESH:D015431), hypertension (MESH:D006973)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956978/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956978/full.md

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Source: https://tomesphere.com/paper/PMC12956978