# Sarcoma at the Site of a Transponder Implant in a Standing’s Day Gecko (Phelsuma standingi): A Case Report

**Authors:** Madeleine V. Thompson, Tessa Kell, Stefan M. Keller, Jasmine Rosario, Jenessa Gjeltema

PMC · DOI: 10.1155/crve/1376178 · Case Reports in Veterinary Medicine · 2026-03-03

## TL;DR

A gecko developed a tumor near a microchip implant, raising concerns about possible links between implants and cancer in reptiles.

## Contribution

This is the first reported case of a transponder-associated sarcoma in a reptile.

## Key findings

- A sarcoma was found surrounding a passive integrated transponder in a gecko.
- The tumor invaded muscle, fat, and bone near the implant site.
- A causal link between the transponder and the tumor could not be confirmed.

## Abstract

A 26‐year‐old female Standing’s day gecko (Phelsuma standingi) was presented for evaluation of a mass on the right caudolateral trunk and was subsequently euthanized. Necropsy revealed a neoplastic mass surrounding a passive integrated transponder at the body wall. Histopathology of the mass was consistent with a sarcoma and was characterized by whorls of fusiform neoplastic cells invading the muscle, adipose, and bone of the coelomic wall. Given its proximity to the transponder and the degree to which it encompassed the device, the sarcoma was inferred to be transponder‐associated. However, further conclusions regarding a causal relationship between the transponder implant and the neoplastic mass cannot be drawn based on this single case. This report describes the clinical presentation and pathologic findings for a microchip‐associated neoplasia in a reptile.

## Linked entities

- **Diseases:** sarcoma (MONDO:0005089)
- **Species:** Phelsuma standingi (taxon 143530)

## Full-text entities

- **Genes:** Trp53-ps (transformation related protein 53, pseudogene) [NCBI Gene 22060]
- **Diseases:** cataracts (MESH:D002386), tracheal chondrosarcoma (MESH:D002813), scoliosis (MESH:D012600), carcinogenic (MESH:D011230), infection (MESH:D007239), dehydration (MESH:D003681), leukopenia (MESH:D007970), tumorigenesis (MESH:D063646), stifle osteoarthritis (MESH:D010003), Sarcoma (MESH:D012509), wounds (MESH:D014947), muscle wasting (MESH:D009133), inflammatory (MESH:D007249), chondroblastic osteosarcoma (MESH:D012516), periocular myxosarcoma (MESH:D009236), fibrosarcoma (MESH:D005354), malignant tumors (MESH:D009369), adenocarcinomas (MESH:D000230), amelanotic melanoma (MESH:D018328), Sertoli cell tumors (MESH:D012707), secondary hyperparathyroidism (MESH:D006962)
- **Chemicals:** trimethoprim/sulfamethoxazole (MESH:D015662), tramadol (MESH:D014147), calcium (MESH:D002118), Postformalin (-), Aluminum (MESH:D000535), activated charcoal (MESH:D002606)
- **Species:** Pogona vitticeps (central bearded dragon, species) [taxon 103695], Tenebrio molitor (yellow mealworm, species) [taxon 7067], Xenopus laevis (African clawed frog, species) [taxon 8355], Ctenosaura similis (black iguana, species) [taxon 51212], Soricidae (shrews, family) [taxon 9376], Lepidosauria (lepidosaurs, class) [taxon 8504], Feline leukemia virus (no rank) [taxon 11768], Ambystoma mexicanum (axolotl, species) [taxon 8296], Salvator merianae (Argentine black and white tegu, species) [taxon 96440], Cryptomys hottentotus (African mole rat, species) [taxon 10175], Varanus varius (lace monitor, species) [taxon 8559], Felis catus (cat, species) [taxon 9685], Homo sapiens (human, species) [taxon 9606], Galleria mellonella (greater wax moth, species) [taxon 7137], Acheta domesticus (house cricket, species) [taxon 6997], Serpentes (snakes, infraorder) [taxon 8570], Mus musculus (house mouse, species) [taxon 10090], Canis lupus familiaris (dog, subspecies) [taxon 9615], Varanus acanthurus (species) [taxon 62035]
- **Mutations:** C-28 C

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956844/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956844/full.md

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Source: https://tomesphere.com/paper/PMC12956844