# Impact of cold air exposure on respiratory physiology during light‐to‐moderate physical activity in healthy adults

**Authors:** Christopher L. Chapman, Adam W. Potter, Erica A. Schafer, Karl E. Friedl, J. Luke Pryor, David P. Looney

PMC · DOI: 10.14814/phy2.70801 · Physiological Reports · 2026-03-03

## TL;DR

Cold air increases breathing during light exercise, mainly by making each breath deeper, which could affect performance in cold environments.

## Contribution

This study reveals how cold air specifically increases ventilation during physical activity in healthy adults.

## Key findings

- Minute ventilation was significantly higher at 0°C compared to 10°C and 20°C.
- Increased ventilation at 0°C was mainly due to larger tidal volumes.
- Heart rate was modestly affected by temperature, but breathing frequency and perceived exertion were not.

## Abstract

Working in cold environments presents unique physiological challenges, and this study sought to investigate the specific impacts of cold air exposure on ventilation during light‐to‐moderate physical activity simulating occupational work demands. Fourteen healthy adults (3 females; age: 24 ± 6 years) completed five 20‐min treadmill walking bouts across three environmental conditions (20°C, 10°C, and 0°C) in a randomized, crossover design. Respiratory variables, including minute ventilation (VE), breathing frequency (RR), and tidal volume (Vt), were measured, as well as heart rate (HR) and ratings of perceived exertion (RPE). Data were analyzed using repeated‐measures ANOVA. VE was significantly higher at 0°C compared to both 10°C (mean difference [Δ]: +2.08 L·min−1, p < 0.001) and 20°C (Δ: +1.62 L·min−1, p < 0.001) during the final exercise stage. This increased ventilation was primarily driven by a significant increase in Vt at 0°C compared to 10°C (Δ: +0.11 L, p = 0.002) and 20°C (Δ: +0.13 L, p = 0.002). RR and RPE did not differ between conditions, while HR was modestly affected by temperature. Cold air exposure significantly alters ventilatory patterns during light‐to‐moderate physical activity. Increased ventilation observed at colder temperatures is primarily mediated by increases in Vt. These findings provide insight into acute cold‐air respiration and highlight implications for performance in austere environments.

## Full-text entities

- **Genes:** TRPM8 (transient receptor potential cation channel subfamily M member 8) [NCBI Gene 79054] {aka LTRPC6, LTrpC-6, TRPP8, trp-p8}, TRPA1 (transient receptor potential cation channel subfamily A member 1) [NCBI Gene 8989] {aka ANKTM1, FEPS, FEPS1, p120}
- **Diseases:** inflammation (MESH:D007249), shortness of breath (MESH:D004417), asthma (MESH:D001249), bronchospasm (MESH:D001986), airway irritation (MESH:D000402), hypothermia (MESH:D007035), EIA (MESH:D001250), cold injuries (MESH:D000067390), hyperventilation (MESH:D006985), dehydration (MESH:D003681), musculoskeletal injuries (MESH:D009140), Raynaud's syndrome (MESH:D011928), hypocapnia (MESH:D016857), myopathic, (MESH:D009135)
- **Chemicals:** histamine (MESH:D006632), oxygen (MESH:D010100), water (MESH:D014867), VCO2 (-), caffeine (MESH:D002110), furosemide (MESH:D005665), nicotine (MESH:D009538), carbon dioxide (MESH:D002245), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606], Rangifer tarandus (caribou, species) [taxon 9870]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956833/full.md

## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956833/full.md

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Source: https://tomesphere.com/paper/PMC12956833