# Bridging Minds and Behaviours: Patient Empowerment Mediates Psychological Factors and Diabetes Self‐Management

**Authors:** Shujie Liu, Fei Chen, Fangli Tang, Wenjun Wang, Xiaodan Yuan, Dan Cheng, Yetong Wang, Qingqing Lou

PMC · DOI: 10.1002/edm2.70183 · Endocrinology, Diabetes & Metabolism · 2026-03-03

## TL;DR

This study shows that patient empowerment connects psychological factors like stress and personality to better diabetes management and blood sugar control.

## Contribution

The study identifies patient empowerment as a key mediator linking psychosocial factors to diabetes self-management and glycemic control in type 2 diabetes patients.

## Key findings

- Patient empowerment mediates the relationship between psychological factors and diabetes self-management behaviors and HbA1c.
- Type D personality and diabetes distress are significant risk factors for low patient empowerment.
- Empowerment-focused interventions could improve diabetes management and glycemic control.

## Abstract

This multicenter cross‐sectional study was designed to verify whether patient empowerment mediates the relationship between psychosocial factors and diabetes self‐management behaviours and HbA1c. Patient empowerment is a key factor improving diabetes management. The mechanism underneath is less clear.

We conducted a multicenter cross‐sectional study of 2005 type 2 diabetes from five university hospitals across diverse Chinese regions between December 2022 and May 2023. Demographic and lab values came from electronic medical record systems (EMS) while psychological factors were assessed via self‐administered digital scales on a WeChat mini‐program. The study examined patient empowerment's mediating role between psychological factors (Type D personality, DD, attitudes, subjective norms, perceived control, behaviour change intentions) and diabetes outcomes using mediation and chain mediation analyses.

Patients with lower empowerment scores had shorter disease duration, poorer glycemic control, a higher prevalence of dyslipidemia and multiple complications, and greater socioeconomic disadvantage. Type D personality (OR = 2.201, p < 0.001) and diabetes distress (DD, OR = 1.053, p < 0.001) were identified as independent risk factors for low empowerment. Moreover, patient empowerment significantly mediated the associations between psychosocial factors and both self‐management behaviours and HbA1c. Mediation analyses showed significant indirect effects of Type D personality (γ = −0.794, p < 0.001), DD (γ = −0.050, p = 0.024), attitude toward behaviour change (γ = 0.470, p < 0.001), subjective norm (γ = 0.287, p < 0.001), perceived behavioural control (γ = 0.489, p < 0.001) and behavioural intention (γ = 0.458, p < 0.001) on self‐management behaviours through empowerment.

Patient empowerment functions as a critical mediator linking psychosocial factors to self‐management behaviours and glycemic control in individuals with type 2 diabetes. Type D personality and DD represent important risk factors for low empowerment. These findings suggest that patient empowerment‐focused interventions may enhance diabetes self‐management and glycemic control.

This graphical abstract illustrates the conceptual framework of the study, showing how psychosocial factors influence glycemic control with type 2 diabetes through patient empowerment and self‐management behaviours.

## Linked entities

- **Diseases:** type 2 diabetes (MONDO:0005148), dyslipidemia (MONDO:0002525)

## Full-text entities

- **Diseases:** communication impairments (MESH:D003147), chronic disease (MESH:D002908), Type D personality (MESH:D010554), Type 2 Diabetes (MESH:D003924), cardiovascular disease (MESH:D002318), end-stage renal disease (MESH:D007676), hypertension (MESH:D006973), cardiac, hepatic, renal or cerebrovascular (MESH:D066126), DD (MESH:D012128), retinopathy (MESH:D058437), NA (MESH:D019964), Diabetes (MESH:D003920), Type D (MESH:C562420), physical disabilities (MESH:D059445), visual impairments (MESH:D014786), dyslipidemia (MESH:D050171), DD (MESH:C536170), Disease (MESH:D004194)
- **Chemicals:** glucose (MESH:D005947), alcohol (MESH:D000438), DES (MESH:D004054), lipid (MESH:D008055), Glycated (-), blood glucose (MESH:D001786), cortisol (MESH:D006854)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12956832/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956832/full.md

## References

44 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956832/full.md

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Source: https://tomesphere.com/paper/PMC12956832