# A paradigm shift and practical exploration in veterinary pharmacology and toxicology teaching reform in China’s frontier regions under AI empowerment

**Authors:** Meiquan Li, Yuru Ma, Yanli Du, Xiao Wang, Hongyan Zhang

PMC · DOI: 10.3389/fvets.2026.1736521 · Frontiers in Veterinary Science · 2026-02-18

## TL;DR

This paper proposes an AI-powered teaching reform for veterinary pharmacology and toxicology in China's border regions to better address local health and safety challenges.

## Contribution

The study introduces an AI-driven educational system integrating virtual reality and regional data to improve veterinary training in frontier areas.

## Key findings

- An intelligent teaching system was developed using dynamic knowledge graphs and virtual simulations for plateau pharmacology and toxicology.
- The reform emphasizes integrating drug efficacy and safety evaluation to meet regional veterinary needs and health paradigms.
- A multidimensional evaluation framework was created to assess both therapeutic and toxicological competencies.

## Abstract

Veterinary pharmacology and toxicology education in Southwest China’s border regions faces unique challenges, including plateau animal diseases and transnational epidemic control, and the need for strict veterinary drug residue monitoring and toxic risk prevention, which traditional teaching methods cannot adequately address. This study explores an AI-driven educational reform centered on data-driven instruction and virtual reality integration. By constructing dynamic regional knowledge graphs, personalized learning pathways, and high-fidelity simulation platforms for plateau pharmacology experiments, clinical decision-making, and toxicological risk assessment, we establish an intelligent teaching system tailored to frontier characteristics. The system deeply integrates pharmacological efficacy research with toxicological safety evaluation, an integration emphasized as the cornerstone of veterinary practice in ensuring drug safety, controlling residue risks, and safeguarding the “One World, One Health” paradigm. The reform also addresses digital divide risks while developing a multidimensional evaluation framework covering both therapeutic effectiveness and toxicological safety competencies. This paradigm shift aims to enhance the quality of veterinary pharmacology and toxicology education in border regions by providing systematic solutions for cultivating professionals capable of balancing drug efficacy and safety, addressing regional toxicological challenges, and serving regional development needs.

## Full-text entities

- **Diseases:** foot-and-mouth disease (MESH:D005536), animal diseases (MESH:D000820), toxicities (MESH:D064420), hypoxia (MESH:D000860), poisoning (MESH:D011041), high-altitude sickness (MESH:D000532), Deficiencies (MESH:D007153), respiratory disease (MESH:D012140), swine fever (MESH:D006691), parasitic diseases (MESH:D010272), drug (MESH:D000081015), coccidiosis (MESH:D003048)
- **Chemicals:** ivermectin (MESH:D007559)
- **Species:** Homo sapiens (human, species) [taxon 9606], Gallus gallus (bantam, species) [taxon 9031], Sus scrofa (pig, species) [taxon 9823], Ovis aries (domestic sheep, species) [taxon 9940], Escherichia coli (E. coli, species) [taxon 562], Bos taurus (bovine, species) [taxon 9913]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956618/full.md

## References

59 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956618/full.md

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Source: https://tomesphere.com/paper/PMC12956618