# Mortality risk effects of ozone and meteorological factors: a 10-year time-series study

**Authors:** Na Cao, Xiaojuan Yang, Yifei Chen, Lifang Zhao, Shuai Guo, Rui Li, Guiming Zhu, Lin Ma, Zhihong Zhang

PMC · DOI: 10.3389/fpubh.2026.1742521 · Frontiers in Public Health · 2026-02-18

## TL;DR

This study shows that ozone exposure increases mortality risk, especially when combined with certain weather conditions like temperature and sunshine.

## Contribution

The study identifies specific meteorological factors that modify ozone-related mortality risks over a 10-year period in Taiyuan, China.

## Key findings

- Ozone exposure significantly contributes to all-cause, respiratory, and circulatory mortality with lagged effects.
- Sunshine duration, season, and temperature are key factors modifying the ozone-mortality relationship.
- Interactive health risks are more pronounced among females and older adults.

## Abstract

Tropospheric ozone (O₃) is increasingly becoming the dominant urban air pollutant in China, posing significant public health risks that are exacerbated by meteorological conditions. A clear understanding of how O₃-related health effects are modified by atmospheric factors is crucial for targeted risk mitigation.

This ten-year time-series study (2013–2022) was conducted in Taiyuan, China. We analyzed data on daily O₃ concentrations, meteorological factors, and all-cause and cause-specific mortality. The analysis employed Generalized Additive Models (GAMs) to assess the lagged effects of O₃ exposure on mortality and to investigate the interactions between O₃ and key atmospheric determinants, including temperature, sunshine duration, and season.

The study revealed distinct patterns of O₃-related mortality risk modified by meteorological conditions. The 10-year average daily O₃ concentration was 92.92 μg/m3. O₃ exposure significantly contributed to all-cause, respiratory, and circulatory mortality with lagged effects. While atmospheric pressure, sunshine duration, temperature, and season all influenced the O₃-mortality relationship, the effect was primarily modified through significant interactions with sunshine duration, season, and temperature. These interactive health risks were more pronounced among females and the older adults.

Our study provides strong evidence that O3 increases the risk of all-cause, respiratory and circulatory mortality in the population. In addition, there were interactions between meteorological factors and O3, primarily involving sunshine duration, season and temperature.

## Linked entities

- **Chemicals:** ozone (PubChem CID 24823)

## Full-text entities

- **Diseases:** respiratory disease (MESH:D012140), coronary heart disease (MESH:D003327), circulatory disease (MESH:D012769), inflammation (MESH:D007249), lung injury (MESH:D055370), lung cancer (MESH:D008175), diabetes mellitus (MESH:D003920), malignant tumors (MESH:D009369), neurological diseases (MESH:D020271), pulmonary embolism (MESH:D011655), death (MESH:D003643), ischemic heart disease (MESH:D017202), diseases of the respiratory system (MESH:D015619), nervous system disease (MESH:D009422), endothelial (MESH:D005642)
- **Chemicals:** oxygen (MESH:D010100), NO2 (MESH:D009585), CO (MESH:D002248), PM10 (-), O3 (MESH:D010126), SO2 (MESH:D013458)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12956530/full.md

## References

38 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956530/full.md

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Source: https://tomesphere.com/paper/PMC12956530