# A Spinal Epidural Arteriovenous Fistula Treated With Onyx Transarterial and Transvenous Embolization Using the Hemiazygos Vein: A Case Report

**Authors:** Akina Hirohashi, Shunsaku Goto, Takashi Izumi, Masahiro Nishihori, Issei Takeuchi, Shinsuke Muraoka, Hiroki Shimuzu, Satoshi Ito, Nobuhiko Mizutani, Ryuta Saito

PMC · DOI: 10.7759/cureus.102795 · Cureus · 2026-02-01

## TL;DR

A rare spinal artery-vein abnormal connection was successfully treated using a combination of specialized embolization techniques.

## Contribution

A novel endovascular treatment approach combining transarterial and transvenous embolization for complex spinal fistulas is described.

## Key findings

- Combining Onyx transarterial and transvenous embolization improved symptoms in a patient with a complex SEDAVF.
- Persistent symptoms after initial embolization required additional intervention via the hemiazygos vein.
- Accurate preoperative imaging and understanding of vascular anatomy are critical for successful treatment.

## Abstract

A spinal epidural arteriovenous fistula (SEDAVF) often causes dilatation of the epidural venous plexus extending across 1-2 vertebral segments, frequently exhibiting intramedullary venous reflux. Herein, we report a case of SEDAVF characterized by multiple discontinuous dilated epidural venous plexuses extending across seven vertebral segments, accompanied by intradural venous reflux. A 53-year-old woman presented with gait disturbance. Spinal magnetic resonance imaging (MRI) and computed tomography angiography (CTA) revealed spinal cord edema, flow voids, multiple dilated epidural venous plexuses, and intradural venous reflux, leading to a diagnosis of SEDAVF. Treatment was performed based on the assumption that an L2 radiculomedullary vein (RMedV) with intradural reflux was responsible for the symptoms. Accordingly, Onyx transarterial embolization (TAE) was initially administered, but as the patient’s symptoms persisted, we performed another intervention, combining Onyx transvenous embolization (TVE) via the azygos and hemiazygos vein with Onyx TAE, which removed reflux into the RMedV and improved symptoms. Thus, in cases of SEDAVF with multiple dilated venous plexuses extending across several vertebral levels, identifying the responsible lesion and fully understanding the vascular anatomy is needed to ensure appropriate treatment. An endovascular treatment strategy focused on eliminating intravertebral reflux may lead to symptomatic improvement. As such, meticulous preoperative imaging interpretation and accurate identification of the symptom-causing lesions are crucial.

## Full-text entities

- **Diseases:** compressive myelopathy (MESH:D013117), spinal arteriovenous shunt lesions (MESH:C562451), neurological (MESH:D009461), myelopathy (MESH:D013118), congenital vascular disorder (MESH:D020785), paraplegia (MESH:D010264), bladder or bowel dysfunction (MESH:D001745), congenital disorder (MESH:D009358), disc herniation (MESH:D007405), Arteriovenous Fistula (MESH:D001164), neurological deterioration (MESH:D009422), gait disturbance (MESH:D020233), SAMS (MESH:D001165), cutaneous lesions (MESH:D009059), spinal cord infarction (MESH:D007238), venous congestive myelopathy (MESH:D006940), venous hypertension (MESH:D014647), RMedV (MESH:D000071078), congestive myelopathy (MESH:D002311), diminished pain (MESH:D020886), muscle weakness (MESH:D018908), spinal canal stenosis (MESH:D013130), vascular disorder (MESH:D002561), radiculopathy (MESH:D011843), spinal cord edema (MESH:D004487), reflux (MESH:D005764), trauma (MESH:D014947), thrombosis (MESH:D013927), lower leg pain (MESH:D010146), venous outflow obstruction (MESH:D006502)
- **Chemicals:** Onyx 18 (MESH:C558446), Onyx 34 (MESH:C000598428), Onyx (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12956487/full.md

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Source: https://tomesphere.com/paper/PMC12956487