# Posterior Mitral Valve Acute Infective Endocarditis Complicated With Brain Abscess and Infection-Related Glomerulonephritis: A Case Report

## TL;DR

A woman with a heart infection caused by Staphylococcus aureus developed brain abscesses and kidney issues, but fully recovered after treatment with antibiotics and dental surgery.

## Contribution

This case report highlights the rare systemic complications of infective endocarditis and the importance of multidisciplinary care.

## Key findings

- The patient's infection led to cerebral abscesses and acute kidney injury.
- Treatment with antibiotics and dental intervention led to full recovery.
- Follow-up imaging showed resolution of heart and brain complications.

## Abstract

We report the case of a 48-year-old previously unevaluated woman who presented with a short febrile illness with multi-organ involvement and was later diagnosed with acute methicillin-sensitive Staphylococcus aureus infective endocarditis of the posterior mitral valve. Her illness was complicated by septic embolization, leading to cerebral abscesses and infection-related glomerulonephritis, causing acute kidney injury. She had multiple septic teeth, which were thought to be the source of bacteremia. She was managed with multidisciplinary input involving cardiology, neurology, neurosurgery, microbiology, and oral maxillofacial surgery. Six weeks of intravenous antibiotics and removal of dental foci resulted in complete clinical and biochemical recovery. Follow-up transesophageal echocardiogram demonstrated resolution of the vegetation, and interval imaging showed a reduction in the size of the brain abscess. This case highlights the importance of early recognition of infective endocarditis and the need for multidisciplinary care in the presence of systemic complications.