This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies
Abstract
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Taxonomy
TopicsHeat shock proteins research · Protease and Inhibitor Mechanisms · Monoclonal and Polyclonal Antibodies Research
After this article [1] was published, concerns were raised regarding the statistical analyses and interpretation of the results. Specifically:
The corresponding author stated that they agreed with the above concerns for the statistical analyses. During post-publication correspondence, they provided multiple statistical re-analyses for all graphs in [1]. A member of the PLOS One Editorial Board reviewed the author’s responses and repeated statistical analyses, and stated that these did not resolve the concerns raised for the statistical methods and that the re-analyses raised additional concerns for the reliability of the results reported.
Following editorial assessment, the PLOS One Editors concluded that the article does not meet the journal’s third and fourth criteria for publication [2]. In light of the above concerns, which call into question the validity and reliability of the published results, the PLOS One Editors retract this article.
All authors agreed with the retraction and apologize for the issues with the published article.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Jaffaraghaei M, Ghafouri H, Vaziri B, Taheri M, Talebkhan Y, Heravi M, et al. RETRACTED: Induction of heat shock protein expression in SP 2/0 transgenic cells and its effect on the production of monoclonal antibodies. P Lo S One. 2024;19(5):e 0300702. doi: 10.1371/journal.pone.0300702 38696377 PMC 11065310 · doi ↗ · pubmed ↗
- 2P Lo S One. Criteria for Publication [Internet] Available from: https://journals.plos.org/plosone/s/criteria-for-publication [Accessed February 2026]